| 肺癌根治术后肺部感染的相关因素分析 |
| |
| 引用本文： | 刘东东,沈剑,黄思远,王海涛.肺癌根治术后肺部感染的相关因素分析[J].中华全科医学,2021,19(4):550-553. |
| |
| 作者姓名： | 刘东东 沈剑 黄思远 王海涛 |
| |
| 作者单位： | 浙江省人民医院/杭州医学院附属人民医院心胸外科，浙江 杭州 310014 |
| |
| 基金项目： | 浙江省医药卫生科技计划项目(2020KY009);浙江省基础公益研究计划项目(LY20H010005)。 |
| |
| 摘 要： | 目的 探讨肺癌根治术后肺部感染的相关影响因素，为预防和降低肺癌根治术后肺部感染几率提供方法依据。 方法 选取2018年2月—2020年2月在浙江省人民医院心胸外科行肺癌根治术的患者82例，根据是否发生肺部感染分为肺部感染组(23例)和非肺部感染组(59例)。收集和整理患者的一般临床资料，分析肺癌根治术后肺部感染的相关影响因素。 结果 82例患者术后肺部感染发生率为28.05%。单因素分析结果显示患者的性别、是否伴有高血压、术前肺功能、肺叶切除部位、病理类型、病理分期与术后肺部感染无显著相关性(均P>0.05)；年龄(≥60岁)、切口VAS评分(4~10分)、长期吸烟史、合并慢性阻塞性肺疾病(COPD)、糖尿病(DM)、手术时间(≥3 h)、手术方式(传统开胸手术)、机械通气时间(≥6 h)、胸腔引流管留置时间(≥4 d)与肺部感染密切相关(均P < 0.05)。Logistic多因素分析显示，年龄大(≥60岁)、手术时间长(≥3 h)、合并COPD、DM、手术方式(传统开胸手术)、长期吸烟史、切口VAS评分(4~10分)、胸腔引流管留置时间长(≥4 d)是肺癌根治术患者术后发生肺部感染的独立影响因素(均P < 0.05)。 结论 肺癌根治术后肺部感染发生率较高，术后发生肺部感染的影响因素较多，其中年龄大(≥60岁)、手术时间长(≥3 h)、合并COPD、DM、手术方式(传统手术)、长期吸烟史、切口VAS评分(4~10分)、胸腔留置引流时间长(≥4 d)是肺癌根治术患者术后发生肺部感染的危险因素，今后应在临床上针对上述危险因素采取积极处理措施，以降低术后肺部感染发生率。
|
| 关 键 词： | 肺癌 肺癌根治术 肺部感染 影响因素 |
| 收稿时间： | 2020-07-30 |
Analysis of factors related to pulmonary infection after radical resection of lung cancer |
| |
| Authors: | LIU Dong-dong SHEN Jian HUANG Si-yuan WANG Hai-tao |
| |
| Affiliation: | Department of Cardio-thoracic Surgery, Zhejiang Provincial People's Hospital/People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, China |
| |
| Abstract: | Objective To investigate the factors influencing pulmonary infection after radical resection of lung cancer.Methods Eighty-two patients who underwent radical resection of lung cancer in Department of Cardio-thoracic Surgery in Zhejiang Provincial People’s Hospital/People’s Hospital of Hangzhou Medical College were selected from February 2018 to February 2020.Eighty-two cases of lung cancer,according to whether the lung infection can be divided into pulmonary infection(23 cases)and non-pulmonary infection group(59 cases).The general clinical data of the patients were collected.The factors related to lung cancer that affect postoperative pulmonary infection after radical cure were analysed.Results The incidence of postoperative pulmonary infection was 28.05%.Univariate analysis revealed no significant correlation among gender,hypertension,preoperative pulmonary function,lobectomy site,pathological type,pathological stage and postoperative pulmonary infection(all P>0.05).Age(≥60 years old),VAS score of incision(4-10 points),long-term smoking history,combined chronic obstructive pulmonary disease(COPD),diabetes mellitus(DM),operation duratiion(≥3 h),operation method(i.e.,traditional thoracotomy),mechanical ventilation time(≥6 h)and indwelling time of thoracic drainage tube(≥4 days)were closely correlated with pulmonary infection(all P<0.05).Logistic multivariate analysis showed that age(≥60 years old),long operation duration(≥3 h),combined COPD,DM,operation method(traditional thoracotomy),long-term smoking history,VAS score of incision(4-10 points)and long duration of pleural indwelling drainage(≥4 days)were independent influencing factors for postoperative pulmonary infection in patients undergoing radical resection of lung cancer(all P<0.05).Conclusion The incidence of postoperative pulmonary infection is high in lung cancer patients after radical resection pulmonary infection.The risk factors of postoperative pulmonary infection in patients with lung cancer after radical resection are age(≥60 years old),long operation duration(≥3 h),with COPD,with DM(traditional surgery),surgical way,long-term smoking history,VAS score of incision(4-10 points)and long chest drainage timeline(≥4 days).These risk factors should be paid more attentions so as to reduce the incidence of postoperative pulmonary infection. |
| |
| Keywords: | Lung cancer Radical resection of lung cancer Pulmonary infection Influencing factor |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中华全科医学》浏览原始摘要信息 |
|
点击此处可从《中华全科医学》下载全文 |
|
