| 龟地散与钙剂对去放巢大鼠骨重,骨密度,骨强度的影响 |
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| 引用本文： | 王学娅,戴力明.龟地散与钙剂对去放巢大鼠骨重,骨密度,骨强度的影响[J].中国骨质疏松杂志,2000,6(1):74-77. |
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| 作者姓名： | 王学娅 戴力明 |
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| 作者单位： | 辽宁省基础医学研究所 |
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| 摘 要： | 使用补肾健骨中药龟地散对切除卵巢的雌性大鼠进行不同剂量的药物治疗，并与模型对照组和钙剂组进行比较。实验结果表明：龟地散显提高模型对照组大鼬有密度值（Ｐ〈０．０５）和骨矿含量（Ｐ〈０．０５），从而抑制骨矿溶解和丢失。与模型对照组相比，龟地散明显增加骨质疏松大鼠的骨重（Ｐ〈０．０１），并且对大鼠的骨长、骨直径、骨面积和体重也有一定的影响。龟地散还具有显提高大鼠骨强度（Ｐ〈０．０１）等方面的作用。单
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| 关 键 词： | 龟板 熟地 钙剂 骨质疏松 卵巢切除术 |
Effects of Gui-Di Powder and calcium on bone weight,bone mineral density,and bone strength in ovariectomized rats |
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| Wang Xueya,Dai Liming,Han Jian,Guo Jian,Cui Liandong,Xiao Ping.Effects of Gui-Di Powder and calcium on bone weight,bone mineral density,and bone strength in ovariectomized rats[J].Chinese Journal of Osteoporosis,2000,6(1):74-77. |
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| Authors: | Wang Xueya Dai Liming Han Jian Guo Jian Cui Liandong Xiao Ping |
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| Abstract: | Ovariectomized
female adult rats were treated with kidney tonifying herbs (Gui-Di Powder,GDP) in
different dosages,and compared with ovariectomized group (OVX) and calcium-treated
group.The results showed that GDP could remarkably increase bone density (P<0.05) and
bone minerals (P<0.05) in OVX rats.And it could significantly inhibit the dissolution
and loss of bone minerals in comparison with the OVX.Moreover,it had definite effects on
bone length,bone diameter,bone area and body weight in rats.Experiments also showed that
GDP could greatly enhance bone strength in rats.Supplementation of calcium did not greatly
change the parameters except bone strength. |
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| Keywords: | Tortoise plastron Rehmannia glutinosa Calcium Ovariectomy Osteoporosi |
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