| CT与MR多序列融合指导胶质瘤靶区勾画 |
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| 引用本文： | 杨 军1,王颖拓2,李卓然1,郭文灵1,牛红蕊1,李小瑞1. CT与MR多序列融合指导胶质瘤靶区勾画[J]. 现代肿瘤医学, 2020, 0(8): 1353-1357. DOI: 10.3969/j.issn.1672-4992.2020.08.028 |
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| 作者姓名： | 杨 军1 王颖拓2 李卓然1 郭文灵1 牛红蕊1 李小瑞1 |
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| 作者单位： | 1.新乡医学院第一附属医院肿瘤科，河南 新乡 453100;2.南阳市中心医院放疗科，河南 南阳 473000 |
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| 摘 要： | 目的:探讨CT与MR图像融合在脑胶质瘤术后放疗靶区勾画中的应用价值。方法:收集首诊为脑胶质瘤的30例患者进行术后IMRT，基于颅内外标记法的图像配准融合算法进行CT-MR图像融合，并分别根据CT图像及融合图像由资深放疗医师勾画靶区及危及器官，分组进行t检验比较其体积差异。计算CT及CT-MR图像上相应标记点的距离，并计算其体积重合度及中心位置距离。结果:采用颅内外标记法进行图像融合有着较高融合精度，融合误差均小于2 mm。Ⅲ-Ⅳ级胶质瘤组GTVCT比GTVMR+CT显著性减少，分别为GTVCT:（72.23±36.74） cm3，GTVMR+CT:（104.23±32.64） cm3（P=0.043<0.05）；CTVCT比CTVMR+CT也显著性降低，分别为CTVCT:（244.24±65.37） cm3，CTVMR+CT:（346.39±51.54） cm3 （P=0.047<0.05）。CT图像与融合图像的CTV中心位置变化最大，为（7.87±11.54） mm，其次为GTV、脑干，视交叉中心位置变化最小。结论:CT-MR图像融合有助于减少靶区勾画差异性，特别是对有水肿区存在及术后肿瘤残存者价值更大。
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| 关 键 词： | 体层摄影术 X线算机 磁共振成像 图像融合 脑瘤/放射疗法 |
Multi-sequence fusion of CT and MR to guide the delineation of glioma target |
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| Yang Jun1,Wang Yingtuo2,Li Zhuoran1,Guo Wenling1,Niu Hongrui1,Li Xiaorui1. Multi-sequence fusion of CT and MR to guide the delineation of glioma target[J]. Journal of Modern Oncology, 2020, 0(8): 1353-1357. DOI: 10.3969/j.issn.1672-4992.2020.08.028 |
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| Authors: | Yang Jun1 Wang Yingtuo2 Li Zhuoran1 Guo Wenling1 Niu Hongrui1 Li Xiaorui1 |
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| Affiliation: | 1.Department of Oncology,the First Affiliated Hospital of Xinxiang Medical College,Henan Xinxiang 453100,China；2.Department of Radiotherapy,Nanyang Central Hospital,Henan Nanyang 473000,China. |
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| Abstract: | Objective:To investigate the value of CT and MR image fusion in the delineation of radiotherapy target after glioma surgery.Methods:Thirty patients with gliomas were enrolled for postoperative IMRT.The image registration fusion algorithm based on intracranial and extracranial markers was used for CT-MR image fusion.The images were used by senior radiotherapy physicians based on CT images and fused images.Target area and organs at risk were grouped for t-test to compare their volume differences.Calculate the distance of the corresponding points on the CT and CT-MR images,and calculate the volume coincidence degree and the center position distance.Results:Image fusion using intracranial and extracranial markers had a high fusion accuracy,and the fusion error was less than 2 mm.Among them,the GTVCT of the Ⅲ-Ⅳglioma group was significantly less than that of GTVMR+CT［(72.23±36.74) cm3 vs (104.23±32.64) cm3］ (P=0.043<0.05).CTVCT was also significantly decreased than CTVMR+CT［(244.24±65.37) cm3 vs (346.39±51.54) cm3］ (P=0.047<0.05).In addition,the CTV center position of the CT image and the fused image changed the most,being (7.87±11.54) mm,followed by GTV and brainstem,and the position of the optic chiasm was the smallest.Conclusion:CT-MR image fusion can help to reduce the difference of target delineation,especially for the presence of edema and postoperative tumor residual. |
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| Keywords: | tomography X-ray machine magnetic resonance imaging image fusion brain tumor/radiation therapy |
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