| 微透镜治疗病毒性角膜炎并发角膜穿孔的临床疗效 |
| |
| 引用本文： | 杨红,赵洪超,王琼,徐英男,薛劲松.微透镜治疗病毒性角膜炎并发角膜穿孔的临床疗效[J].眼科,2020,29(6):426-429. |
| |
| 作者姓名： | 杨红 赵洪超 王琼 徐英男 薛劲松 |
| |
| 作者单位： | 1.玉溪市人民医院眼科，云南 653100；2 南京医科大学附属眼科医院 210000 |
| |
| 摘 要： | 目的 探讨来源于全飞秒激光小切口角膜基质透镜取出术（small incision lenticule extraction，SMILE）的微透镜治疗病毒性角膜炎并发穿孔的临床疗效。设计 回顾性病例系列。研究对象 2015年4月至2018年12月南京医科大学眼科医院收治的病毒性角膜炎并发角膜穿孔的患者19例（19眼）。方法 将裂孔清创形成碗状植床，选择中央厚度大于100 μm的透镜，用钻环在显微镜下钻取比创面大1 mm的透镜，10-0尼龙线将透镜固定于植床表面，根据植床深度填塞植片至角膜表面轻微隆起，给予佩戴绷带镜。术后6个月，观察患者最佳矫正视力、裂孔修补及植片贴附情况。主要指标 术后最佳矫正视力、裂孔修补及植片贴附情况。结果 19眼角膜穿孔均成功修补，12眼最佳矫正视力不同程度的提升，其中0.02~0.15者8例，0.2~0.4者4例，在术后随访6个月期间，19眼均未见病毒性角膜炎复发，无其他菌群感染，所有植片均贴附良好。结论 SMILE手术来源的微透镜是治疗病毒性角膜炎并穿孔安全有效的植片选择。
|
| 关 键 词： | 病毒性角膜炎 角膜穿孔 全飞秒激光小切口角膜基质透镜取出术 微透镜 |
| 收稿时间： | 2019-09-24 |
Clinical efficacy of lenticule on viral keratitis with perforation |
| |
| Yang Hong,Zhao Hongchao,Wang Qiong,Xu Yingnan,Xue Jinsong.Clinical efficacy of lenticule on viral keratitis with perforation[J].Ophthalmology in China,2020,29(6):426-429. |
| |
| Authors: | Yang Hong Zhao Hongchao Wang Qiong Xu Yingnan Xue Jinsong |
| |
| Affiliation: | 1 Yuxi People's Hospital, Yuxi 653100, Yunnan Province, China; 2 Eye Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, China |
| |
| Abstract: | Objective To observe the clinical efficacy of the small incision lenticule extraction (SMILE)-derived lenticule for the viral keratitis with perforation. Design Retrospective case series. Participants 19 patients (19 eyes) of viral keratitis with perforation in the Affiliated Eye Hospital of Nanjing Medical University from April 2015 to December 2018. Methods Debride the gap to form a bowl-shaped planting bed. Selecting the lenticule with a central thickness more than 100 microns, and drill the lenticule with a drill ring to make it 1 mm larger than the wound surface under the microscope. The lenticule is fixed on the surface of the implantation bed with 10-0 nylon wire, filling the implants according to the depth of the implantation bed until the corneal surface is slightly elevated, and wearing the bandage len at last. The best postoperative corrected visual acuity, the condition of gap repairing and graft attachment was observed in 6 months after the surgery. Main Outcome Measures The best postoperative corrected visual acuity, the condition of gap repairing and graft attachment. Results All perforations were successfully repaired in 19 eyes. The best corrected visual acuity was improved in 12 eyes, including 8 eyes with 0.02~0.15, and 4 eyes with 0.2~0.4. During the postoperative follow-up for 6 months, no recurrence of viral keratitis was observed in 19 eyes, no other bacterial infection was found, and all eye grafts were attached well. Conclusion SMILE-derived lenticule is a safe, effective implant for treating viral keratitis with perforation. |
| |
| Keywords: | viral keratitis corneal perforation small incision lenticule extraction lenticule |
|
| 点击此处可从《眼科》浏览原始摘要信息 |
|
点击此处可从《眼科》下载全文 |
|
