| 良性多囊性腹膜间皮瘤1例及文献复习 |
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| 引用本文： | 史冠军,王 冰,卢一艳,夏 奥,许洪斌.良性多囊性腹膜间皮瘤1例及文献复习[J].现代肿瘤医学,2020,0(6):997-1000. |
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| 作者姓名： | 史冠军 王 冰 卢一艳 夏 奥 许洪斌 |
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| 作者单位： | 1.航天中心医院黏液瘤科；2.病理科，北京 100041 |
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| 基金项目： | 航天中心医院科研基金项目（编号:YN201909） |
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| 摘 要： | 目的:探讨良性多囊性腹膜间皮瘤（benign multicystic peritoneal mesothelioma，BMPM）临床病理特征、诊断及治疗，提高对该病的认识。方法:回顾性分析我院2019年1月收治的1例BMPM患者的临床资料并复习相关文献。结果:该例患者女性，48岁，主因“反复右下腹疼痛5个月”入院，在全麻下行腹腔镜检查+中转开腹:肿瘤细胞减灭术+腹腔热灌注化疗（cytoreducrive surgery+hyperthermic intraperitoneal chemotherapy,CRS+HIPEC）。术后病理报告示:良性囊性腹膜间皮瘤，免疫组化结果:Calretinin（+），MC（+），WT-1（+），CK（+），Vimentin（+），CK5/6（+），CEA（-），CK7（+），CK20（-），PAX-8（+），ER（-），PR（-）。结论:BMPM临床发病率较低，无典型临床表现且缺乏特异性检查，术前诊断较困难，确诊依靠术后病理及免疫组化结果。CRS+HIPEC是目前首选有效的治疗方法，预后良好，复发率较高但恶变率低。
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| 关 键 词： | 良性多囊性腹膜间皮瘤 肿瘤细胞减灭术 腹腔热灌注化疗 |
Benign multicystic peritoneal mesothelioma:A case report and review of the literature |
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| Shi Guanjun,Wang Bing,Lu Yiyan,Xia Ao,Xu Hongbin.Benign multicystic peritoneal mesothelioma:A case report and review of the literature[J].Journal of Modern Oncology,2020,0(6):997-1000. |
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| Authors: | Shi Guanjun Wang Bing Lu Yiyan Xia Ao Xu Hongbin |
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| Affiliation: | 1.Departmet of Myxoma;2.Department of Pathology,Aerospace Center Hospital,Beijing 100041,China. |
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| Abstract: | Objective:To investigate the clinicopathological features,diagnosis and treatment of benign polycystic peritoneal mesothelioma (BMPM) and to improve the understanding of the disease.Methods:The clinical data of a BMPM patient admitted to our hospital in January 2019 were retrospectively analyzed and relevant literatures were reviewed.Results:The 48-year-old female patient was admitted from the main cause of "repeated right lower abdomen pain for five months".An exploratory laparotomy under general anesthesia was performed:Cytoreducrive surgery+ hyperthermic intraperitoneal chemotherapy (CRS+HIPEC).Postoperative pathological report showed:Cystic peritoneal mesothelioma.Immunohistochemical results showed Calretinin (+),MC (+),WT-1 (+),CK (+),Vimentin (+),CK5/6 (+),CEA (-),CK7 (+),CK20 (-),PAX-8 (+),ER (-),PR (-).Conclusion:BMPM has a low clinical incidence,no typical clinical manifestations and lack of specific examination.Preoperative diagnosis is difficult,and the diagnosis depends on postoperative pathological and immunohistochemical results.CRS+HIPEC is the first choice of effective treatment at present,with good prognosis,low malignant transformation rate but high recurrence rate. |
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| Keywords: | benign polycystic peritoneal mesothelioma cytoreducrive surgery hyperthermic intraperitoneal chemotherapy |
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