Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis |
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| Authors: | Jones-Carson J Vazquez-Torres A Warner T Balish E |
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| Affiliation: | Division of Infectious Diseases, University of Colorado Health Science Center, Denver, Colorado, USA. |
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| Abstract: | ![]()
Although highly susceptible to orogastric candidiasis, T-cell receptor delta- and alpha-chain knockout mice, deficient in gammadelta and alphabeta T cells, respectively, were found to be resistant to disseminated candidiasis of endogenous origin and to acute systemic candidiasis (resulting from intravenous injection). |
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