| 伽玛刀放疗联合局部热疗治疗肝癌与单纯放疗对比的临床回顾性分析 |
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| 引用本文： | 喻刘杨,徐细明,戈,伟,王建国,李玉新,邓君健.伽玛刀放疗联合局部热疗治疗肝癌与单纯放疗对比的临床回顾性分析[J].实用肿瘤学杂志,2013,27(4):313-317. |
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| 作者姓名： | 喻刘杨 徐细明 戈 伟 王建国 李玉新 邓君健 |
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| 作者单位： | 1.武汉大学人民医院肿瘤中心(武汉430060);2.荆门市第二人民医院肿瘤科 |
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| 摘 要： | 目的回顾性分析肝癌伽玛刀放疗联合热疗的疗效是否较单纯放疗的疗效更有优势。方法 回顾性分析荆门市第二人民医院2009年5月—2011年12月原发性肝癌病例65例, 将患者随机分为联合组35例及放疗组30例, 放疗组采用伽玛射线放射治疗, 联合组采用伽玛射线放射治疗, 并且在放疗结束后1小时内给予肝脏肿瘤局部热疗。3个月后进行近期疗效判定, 观察生存质量改善情况、生存率及放疗毒副反应。结果 伽玛刀放疗联合局部热疗治疗肝癌较单纯放疗局部缓解率高、生存质量及症状缓解率高、毒副反应低、总生存期(OS)稍有延长。结论 伽玛刀放疗联合局部热疗较单纯伽玛刀放疗在肿瘤缓解率、生存质量、毒副反应及生存期上都有优势。
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| 收稿时间： | 2013-01-30 |
Clinical retrospective analysis compare the gamma knife radiotherapy combined with local hyperthermia with radiotherapy alone on treatment of liver cancer |
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| YU Liuyang,XU Ximing,GE Wei,WANG Jianguo,LI Yuxin,DENG Junjian.Clinical retrospective analysis compare the gamma knife radiotherapy combined with local hyperthermia with radiotherapy alone on treatment of liver cancer[J].Journal of Practical Oncology,2013,27(4):313-317. |
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| Authors: | YU Liuyang XU Ximing GE Wei WANG Jianguo LI Yuxin DENG Junjian |
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| Affiliation: | 1.Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, China;2.Department of Oncology, Second People′s Hospital of Jingmen City |
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| Abstract: | Objective Retrospective analysis on the efficacy of whether liver cancer g-amma knife radiotherapy combined with hyperthermia is better than the simple radiation therapy.Methods Retrospective analysis of cases were from May 2009 to December 2011 in our Hospital.65 cases of primary liver cancer patients were randomly divided into radiotherapy group(30cases)and combination group(35cases);radiotherapy group was given gamma-ray the r gamma knife radiotherapy;combination group was given the gamma-raythe r gamma knife radiotherapy as well as liver tumor local hyperthermia within one hour after the radiotherapy.We examined the short-term effect, and observed the improvement of life quality, and the survival rate and radiation toxicity after three months.Results Compared with the Gamma knife radiotherapy combined with local hyperthermia treatment and simple radiotherapy of liver cancer, the partial remission rate and symptom relief were higher.Toxicity was lower, and the quality of life was better as well as the total lifetime of OS was slightly longer.Conclusion Gamma knife radiotherapy combined with local hyperthermia is advantage than a simple gamma knife radiotherapy in the area of tumor remission rate, quality of life, toxicity and survival period. |
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