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母亲孕前及分娩前超重肥胖对中学生超重肥胖影响的病例对照研究
引用本文:梁健平,贡梓军,梁月朗,郭嘉佳,杨杰文,刘丽,姚振江.母亲孕前及分娩前超重肥胖对中学生超重肥胖影响的病例对照研究[J].中国学校卫生,2022,43(2):268-273.
作者姓名:梁健平  贡梓军  梁月朗  郭嘉佳  杨杰文  刘丽  姚振江
作者单位:1.广东省广州市中小学卫生健康促进中心学校卫生部, 510180
基金项目:2018年广州市教育科学规划课题项目(201811644);;广州市教育科学规划2017年度重点课题项目(1201721333);;2018年度国家自然科学基金资助项目(81874271);
摘    要:目的 探讨广州市母亲孕前及分娩前超重肥胖对子代中学时期超重肥胖的影响,为预防中学生肥胖提供科学依据.方法 依托广州市中学生常规体检,抽取3所高中、3所初中共3384名学生,将体检中超重肥胖的中学生纳入超重肥胖组(642名),其余学生纳入对照组(2742名),对学生及家长进行问卷调查.使用倾向性评分匹配(propensi...

关 键 词:母亲  超重  肥胖症  病例对照研究  回归分析  学生
收稿时间:2021-07-28

Association between maternal pre-pregnancy and pre-delivery overweight with overweight and obesity of middle school students: a case-control study
Affiliation:1.School Health Department, Guangzhou Primary and Secondary School Health Promotion Center, Guangzhou (510180), China
Abstract:  Objective  To explore the association between maternal pre-pregnancy and pre-delivery overweight with overweight and obesity among offspring during adolescence in Guangzhou, and to provide evidence for child obesity prevention.  Methods  Based on the routine physical examination of primary and secondary school students in Guangzhou, random sampling was used to 6 middle schools and questionnaire survey was conducted among 3 384 students and their parents. Students with overweight and obesity were included in the case group, and the other students were included in the control group. Propensity Score Matching (PSM) was adopted to reduce selection bias. Logistic regression model and χ2 test were used to analyze the data before and after PSM.  Results  The result of univariate analysis showed that there were statistically significant differences between overweight/obese group and the control group by gender, schooling stage (middle and high schools), picky eater, family history of obesity, family monthly income, delivery mode, high birthweight, and gestational weight gain before PSM(χ2=42.38, 10.64, 14.47, 26.85, 10.58, 13.59, 15.53, 20.64, P < 0.05). After PSM, results showed that there were no statistically significant differences between overweight/obese group and the control group in middle and high schools, and mother delivery mode(P>0.05). Logistic regression analysis showed that the risk of overweight and obesity of maternal pre-pregnancy on adolescent offspring was 1.54 times higher than control group (95%CI=1.01-2.36) before PSM, and the overweight and obesity of maternal pre-delivery also increased the risk of overweight and obesity of adolescent offspring(OR=2.35, 95%CI=1.67-3.31). After PSM, maternal overweight and obesity pre-pregnancy (OR=2.17, 95%CI=1.41-3.34) and maternal overweight and obesity pre-delivery(OR=2.99, 95%CI=2.08-4.31) significantly increased the risk of overweight and obesity in adolescent offspring.  Conclusion  Maternal overweight and obesity pre-pregnancy and pre-delivery are associated with increased risk of overweight and obesity in adolescent offspring.
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