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苏州市中小学生腺样体肥大及并发分泌性中耳炎分析
引用本文:方琴,陶朵朵.苏州市中小学生腺样体肥大及并发分泌性中耳炎分析[J].中国学校卫生,2021,42(11):1728.
作者姓名:方琴  陶朵朵
作者单位:苏州大学附属第一医院耳鼻咽喉科,江苏 215006
基金项目:国家自然科学基金项目81600796江苏省科技项目BK20160344
摘    要:  目的  分析苏州市7~16岁中小学生腺样体肥大发病情况及并发分泌性中耳炎危险因素,为临床诊断治疗及预后评估提供参考。  方法  整群分层抽取苏州市2015年1月—2019年12月2 986名7~16岁中小学生为研究对象,采用整群分层抽样调查腺样体肥大疑似病例、磁共振检查确诊的方法,分析7~16岁中小学生腺样体肥大流行病学及并发分泌性中耳炎相关危险因素。  结果  中小学生发生腺样体肥大327例,检出率10.95%。2015—2019年中小学生腺样体肥大检出率呈逐年上升趋势,2019年检出率10.95%高于2015年9.20%、2016年9.95%。男生腺样体肥大检出率(12.29%)高于女生(9.48%)(χ2=6.04, P < 0.05)。7~10岁腺样体肥大检出率(15.08%)高于11~16岁中小学生(6.36%)(χ2=57.93, P < 0.05)。327例腺样体肥大中小学生中,合并分泌性中耳炎20例,合并率为6.12%。合并分泌性中耳炎组年龄低于未合并组,腺样体肥大严重程度高于未合并组,血清IL-4、TNF-α、IgA、IgG、IgM高于未合并组(P值均 < 0.05)。腺样体肥大并发分泌性中耳炎与年龄、严重程度、IL-4、IgG、IgM相关(P值均 < 0.05)。  结论  苏州市7~16岁中小学生腺样体肥大发病率较高,与性别、年龄、发病时间及季节有关,且易并发分泌性中耳炎,应引起全社会足够的重视。

关 键 词:中耳炎    流行病学研究    患病率    回归分析    学生
收稿时间:2021-06-23

Analysis of adenoid hypertrophy and secretory otitis media in primary and middle school students in Suzhou
Affiliation:Department of Otorhinolaryngology, the First Affliated Hospital of Soochow University, Suzhou (215006), Jiangsu Province, China
Abstract:  Objective  To analyze the incidence of adenoid hypertrophy and risk factors for secretory otitis media among primary and middle school students aged 7-16 years in Suzhou, and to provide a reference for its clinical disagnosis, treatment and prognosis.  Methods  The primary and secondary school students aged from 7 to 16 in Suzhou from January 2015 to December 2019 were selected by using cluster stratified sampling, adenoid hypertrophy cases were screened and diagnosed by MR, the epidemiology of adenoid hypertrophy and related risk factors of complicated secretory otitis media were analyzed among participants.  Results  Among 327 cases of adenoid hypertrophy were screened, with a prevalence rate of 10.95%. From 2015 to 2019, the prevalence rate of adenoid hypertrophy among primary and middle school students increased by year. The prevalence rate in 2019 was 10.95% higher than 9.20% in 2015 and 9.95% in 2016. The prevalence rate of adenoid hypertrophy in boys was 12.29%, which was higher than 9.48% in girls(χ2=6.04, P < 0.05). The prevalence rate of adenoid hypertrophy between 7-10 years old was 15.08% and higher than 6.36%(χ2=57.93, P < 0.05) for primary and middle school students aged 11-16. Among the 327 primary and middle school students with adenoid hypertrophy, a total of 20 had secretory otitis media, and the combined rate was 6.12%. The age of the combined secretory otitis media group was younger than that of the non-combined group, the severity of adenoid hypertrophy was higher than that of the non-combined group, and serum IL-4, TNF-α, IgA, IgG, and IgM were higher than those of the non-combined group (P < 0.05). Adenoid hypertrophy complicated with secretory otitis media was associated with age, severity, IL-4, IgG, and IgM (P < 0.05).  Conclusion  The prevalence of adenoid hypertrophy among primary and secondary school students aged 7-16 years in Suzhou is relatively high, which is related to gender, age, time of onset and season. Secretory otitis media in adenoids hypertrophy children and adolescents should attract sufficient attention from the whole society.
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