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COVID-19证据现状对快速建议指南制订的启示与思考
引用本文:曾力楠,张伶俐.COVID-19证据现状对快速建议指南制订的启示与思考[J].协和医学杂志,2021,12(4):544-551.
作者姓名:曾力楠  张伶俐
作者单位:1.四川大学华西第二医院 药学部,成都 610041
基金项目:四川省科技计划项目(重点研发项目)2020YFS0035四川省科技计划项目(重点研发项目)子课题20ZDYF3101
摘    要:随着新型冠状病毒肺炎在全球暴发及快速传播,大量相关研究证据迅速产生。然而,因证据质量参差不齐、证据转化质量不佳、证据转化速度较慢等问题,卫生决策者、临床医生及患者如何作出正确决策面临巨大挑战。基于快速系统评价证据,快速建议指南可及时、有效地将当前最新证据转化为指导临床实践的推荐意见。面对全球突发公共卫生事件,通过构建新型证据生态系统,形成证据从生产、评价到应用、转化的完整闭环,从而提高医疗实践水平、减少卫生资源浪费。

关 键 词:新型冠状病毒肺炎    快速建议指南    循证决策
收稿时间:2021-03-24

Thinking about the Development of Rapid Recommendation Based on the Status of COVID-19 Evidence
Affiliation:1.Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China2.Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China3.Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China4.MAGIC, Oslo, Norway, N-0130
Abstract:With the outbreak and rapid spread of the COVID-19 worldwide, a large amount of relevant research evidence has quickly emerged. However, due to the uneven quality of evidence, poor quality and slow speed of evidence translation, it is a big challenge for health decision-makers, clinicians, and patients to make evidence-based decisions. Based on rapid systematic review of evidence, the rapid advice-guidelines can promptly and effectively transform the latest current evidence into recommendations guiding clinical practice. In the face of global public health emergencies, by building a new type of evidence ecosystem, a completely closed loop of evidence from production and evaluation to application and transformation is formed to improve the level of medical practice and reduce the waste of health resources.
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