| 2013-2015年云南省吸毒人群艾滋病新发感染危险因素分析 |
| |
| 引用本文： | 董莉娟,肖民扬,马艳玲,罗红兵,陈敏,杨朝军,戴洁,杨莉,宋丽军,付丽茹,牛瑾,金晓媚,陈会超.2013-2015年云南省吸毒人群艾滋病新发感染危险因素分析[J].中华疾病控制杂志,2017,21(12):1267-1270. |
| |
| 作者姓名： | 董莉娟 肖民扬 马艳玲 罗红兵 陈敏 杨朝军 戴洁 杨莉 宋丽军 付丽茹 牛瑾 金晓媚 陈会超 |
| |
| 作者单位： | 云南省疾病预防控制中心性病艾滋病防制所, 云南 昆明 650022 |
| |
| 基金项目： | “十二五”国家科技重大专项（2012ZX10001-001） |
| |
| 摘 要： | 目的 了解云南省吸毒人群艾滋病新发感染相关的危险因素，为制定科学有效的防治措施提供参考依据。方法 收集2013-2015年云南省吸毒人群哨点监测样本，筛选出血清学检测新确证为人类免疫缺陷病毒（human immunodeficiency virus，HIV）抗体阳性的样本进行BED捕获酶联免疫方法（BED capture enzyme immunoassay，BED-CEIA）新发感染检测，并结合问卷中人口学资料和相关行为学特征等情况进行危险因素分析。结果 在31 503例样本中，共检出HIV抗体阳性3 424例（含既往阳性2 793例），检出率为10.9%（3 424/31 503），其中，87.3%（2 989/3 424）为男性，12.7%（435/3 424）为女性；新报告的感染者，经BED-CEIA方法检出新发感染者101例，其中男性有90例（89.1%），女性有11例（10.9%），新发感染者平均年龄为31.54岁（16~54岁）；2013-2015年吸毒人群的新发感染率为0.53%。多因素Logistic回归分析结果表明，外籍（主要为缅甸籍）、非汉族和注射吸毒的吸毒者艾滋病新发感染的危险性分别高于本省/外省户籍、汉族和口吸的吸毒者，差异均有统计学意义（均有P<0.05）。结论 应重点关注少数民族、外籍（主要为缅甸籍）和注射吸毒人群，进一步强化落实社区药物维持治疗、同伴教育和艾滋病检测咨询等综合干预措施，以减少艾滋病相关高危行为的发生。
|
| 关 键 词： | 获得性免疫缺陷综合征 危险因素 流行病学方法 |
| 收稿时间： | 2017-06-14 |
Analysis on incidence and risk factors for HIV infection among drug users in Yunnan Province from 2013 to 2015 |
| |
| Affiliation: | Department of STDs & AIDS Prevention, Yunnan Center for Disease Control and Prevention, Kunming 650022, China |
| |
| Abstract: | Objective To determine the related risk factors influencing incidence of human immunodeficiency virus (HIV) infection among drug users(DUs) in Yunnan Province and to provide scientific reference for the prevention and control of acquired immune deficiency syndrome(AIDS). Methods HIV-1 antibody positive serum samples of DUs from drug abuse sentinel sites in Yunnan Province during 2013 to 2015 were collected and tested by BED-capture enzyme immunoassay (BED-CEIA). Questionnaires including demographic and behavioral characteristics were performed among DUs to analyze HIV infection risk factors. Results In 31 503 samples, 3 424 were HIV-1 antibody positive(including 2 793 previous infections) and the positive rate was 10.9%(3 424/31 503).Male and female DUs accounted for 87.3% (2 989/3 424) and 12.7% (435/3 424) respectively. Of total 598 new reported HIV cases, 101 new infections were detected by BED-CEIA, among which 90 (89.1%) were male and 11(10.9%) were female with an average age of 31.54 years old (16-54). HIV-1 incident rate among DUs was 0.53% from 2013 to 2015. The result of multivariate Logistic regression analyses showed that new infection risk among participants with the foreign nationality(Myanmar), non-Han nationality and injection drug use was significantly higher than that among participants with registered permanent residence in or not in Yunnan Province,Han nationality and oral drug use (all P<0.05). Conclusions More attention should be paid to DUs with foreign nationality(Myanmar),non-Han nationality and injection drug use. Comprehensive intervention measures including community maintenance treatment, peer education and HIV testing and counseling should be taken to reduce HIV-1 new infection rate. |
| |
| Keywords: | |
|
| 点击此处可从《中华疾病控制杂志》浏览原始摘要信息 |
|
点击此处可从《中华疾病控制杂志》下载全文 |
|
