| 慢性精神分裂症患者神经认知功能与共情能力的相关性研究 |
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| 引用本文： | 李国华,孟琳琳,黄薇,周勇杰.慢性精神分裂症患者神经认知功能与共情能力的相关性研究[J].现代预防医学,2022,0(24):4495-4499. |
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| 作者姓名： | 李国华 孟琳琳 黄薇 周勇杰 |
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| 作者单位： | 1. 深圳市精神卫生中心/深圳市康宁医院，广东 深圳 518000；2. 山东省临沂市精神卫生中心，山东 临沂 276000 |
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| 摘 要： | 目的 神经认知损伤与共情能力下降是精神分裂症的重要特征。然而，这些损伤之间的关系仍不清楚。本研究探讨精神分裂症患者神经认知状况对共情能力影响。方法 于2018年01月—2019年12月在全国19家精神病院招募慢性精神分裂症住院患者作为研究对象。研究通过神经心理状态评估的可重复电池（RBANS）和人际反应指数（IRI）评估调查对象神经认知及同情能力。采用相关性分析的方法，探讨慢性精神分裂症患者神经认知状况与共情的关联。结果 本研究共纳入1 370例慢性分裂症患者。相关分析发现RBANS 总分（r = 0.108，P＜0.01）、三个认知域:即刻记忆（r = 0.117，P＜0.01）、语言（r = 0.077，P＜0.05）、注意（r = 0.153，P＜0.01）与IRI总分呈正相关。RBANS 总分（r = 0.165，P＜0.01）及五个神经认知领域因子得分, 即刻记忆（r = 0.138，P＜0.01）、视觉广度（r = 0.068，P＜0.05）、语言（r = 0.102，P＜0.05）、注意（r = 0.183，P＜0.01）和延时记忆（r = 0.116，P＜0.01）与观点采择得分呈正相关。此外，年龄（r = - 0.074，P＜0.05）与IRI总分呈负相关关系。但PANSS总分与IRI总分不相关。进一步多元线性回归分析发现，神经认知即刻记忆与注意是观点采择因子的重要影响因素（P＜0.05）。结论 精神分裂症患者共情能力下降与神经认知损伤可能存在线性相关，神经认知损伤越重，共情能力下降越严重。
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| 关 键 词： | 慢性 精神分裂症 神经认知损伤 共情 |
Correlation of neurocognition and empathy in patients with chronic schizophrenia |
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| LI Guo-hua,MENG Lin-lin,HUANG Wei,ZHOU Yong-jie.Correlation of neurocognition and empathy in patients with chronic schizophrenia[J].Modern Preventive Medicine,2022,0(24):4495-4499. |
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| Authors: | LI Guo-hua MENG Lin-lin HUANG Wei ZHOU Yong-jie |
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| Affiliation: | *Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen 518000, China |
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| Abstract: | Objective Neurocognitive impairment and decreased empathy are important clinic characters of schizophrenia. However, the correlation between neurocognitive impairment and decreased empathy remains unclear. This study estimated the effect of neurocognition on empathy in schizophrenia patients. Methods The inpatients with chronic schizophrenia were recruited from 19 psychiatric hospitals across China between January 2018 and December 2019. The repeatable battery for the assessment of neuropsychological status (RBANS) was used to measure the cognitive function. The interpersonal reactivity index (IRI) was used to measure the empathy. Pearson correlation coefficient was used to compute the correlation between neurocognitive status and empathy. Results A total of 1 370 inpatients with chronic schizophrenia were included. The total RBANS score (r=0.108, P<0.01), immediate memory (r=0.117, P<0.01), language (r=0.077, P<0.05), and attention (r=0.153, P<0.01) were positively correlated with the IRI score. The total RBANS score (r=0.165, P<0.01), immediate memory (r=0.138, P<0.01), visuospatial/constructional (r=0.068, P<0.05), language (r=0.102, P<0.05), attention (r=0.183, P<0.01), and delayed memory (r=0.116, P<0.01) were positively correlated with the score of perspective-taking. In addition, age (r=-0.074, P<0.05) was negatively correlated with the total score of IRI. However, the PANSS total score was not correlated with IRI total score. Multiple linear regression analysis showed that neurocognitive immediate memory and attention were important influencing factors for perspective-taking (P<0.05). Conclusion There might be a linear correlation between the decrease of empathy and the neurocognitive impairment in schizophrenics. The more severe the neurocognitive impairment, the more serious the empathy. |
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| Keywords: | Chronic Schizophrenia Neurocognitive impairment Empathy |
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