| 吸烟对慢性阻塞性肺疾病及呼吸道症状的影响 |
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| 引用本文： | 查震球,何玉琢,徐伟,陈叶纪,刘心勇,刘志荣,叶冬青. 吸烟对慢性阻塞性肺疾病及呼吸道症状的影响[J]. 中华疾病控制杂志, 2020, 24(1): 46-51. DOI: 10.16462/j.cnki.zhjbkz.2020.01.010 |
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| 作者姓名： | 查震球 何玉琢 徐伟 陈叶纪 刘心勇 刘志荣 叶冬青 |
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| 作者单位： | 1.230601 合肥, 安徽省疾病预防控制中心慢性非传染性疾病防治科 |
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| 基金项目： | 国家科技重大专项;国家重点研发计划 |
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| 摘 要： | 目的 探讨吸烟对慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)及呼吸道症状的影响。 方法 利用多阶段分层整群随机抽样的方法在安徽5个COPD监测点抽取≥40岁调查对象, 并对其进行问卷调查、身体测量和肺功能检测。利用复杂抽样Logistic回归分析模型分析吸烟对COPD及呼吸道症状的影响。 结果 ≥30包年的吸烟者在总人群中占13.9%(95%CI:10.3%~17.5%, P < 0.001), ≥40年的吸烟者在总人群中占8.5%(95%CI:6.7%~10.3%, P < 0.001)。吸烟者平均吸烟年数为32.4 (95%CI:31.2~33.5)年, 吸烟者日均吸烟量为21.1 (95%CI:19.6~22.7)支/天。调整混杂因素后, COPD和呼吸道症状的患病风险均随吸烟包年和吸烟年数的增加而呈上升趋势(均有Ptrend < 0.001)。 结论 吸烟增加COPD及呼吸道症状的患病风险, 吸烟包年和吸烟年数越多, 慢阻肺和呼吸道症状的患病风险越大。
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| 关 键 词： | 吸烟 慢性阻塞性肺疾病 呼吸道症状 横断面研究 流行病学 |
| 收稿时间： | 2019-07-19 |
Effects of smoking on chronic obstructive pulmonary disease and respiratory symptoms |
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| ZHA Zhen-qiu,HE Yu-zhuo,XU Wei,CHEN Ye-ji,LIU Xin-yong,LIU Zhi-rong,YE Dong-qing. Effects of smoking on chronic obstructive pulmonary disease and respiratory symptoms[J]. Chinese Journal of Disease Control & Prevention, 2020, 24(1): 46-51. DOI: 10.16462/j.cnki.zhjbkz.2020.01.010 |
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| Authors: | ZHA Zhen-qiu HE Yu-zhuo XU Wei CHEN Ye-ji LIU Xin-yong LIU Zhi-rong YE Dong-qing |
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| Affiliation: | 1.Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, China2.Huangshan Center for Disease Control and Prevention, Huangshan 245000, China3.Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, China |
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| Abstract: | Objective To investigate the effects of smoking on chronic obstructive pulmonary disease(COPD)and respiratory symptoms.Methods A multi-stage,stratified cluster sampling strategy was used to select participants aged 40 or older in 5 surveillance points of Anhui Province.Questionnaires,body measurements and spirometry were used to collect data.Based on complex sampling design,Logistic regression model was conducted to analyze the effects of smoking on COPD and respiratory symptoms.Results The smokers who had smoked for≥30 pack-years accounted for 13.9%(95%CI:10.3%-17.5%,P<0.001)of the total population.And the smokers who had smoked for≥40 years accounted for 8.5%(95%CI:6.7%-10.3%,P<0.001)of the total population.On average,one smoker had smoked for 32.4 years(95%CI:31.2-33.5).Average daily cigarette consumption of daily smokers was 21.1 cigarettes(95%CI:19.6-22.7).As shown by multiple-variables Logistic regression analyses,the risk of COPD and respiratory symptoms increased with the increment of smoking pack-years and duration(all Ptrend<0.001).Conclusions Smoking was associated with COPD and respiratory symptoms.The risk of developing COPD and respiratory symptoms was greater with the increment of smoking pack-years and duration. |
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| Keywords: | Smoking Chronic obstructive pulmonary disease Respiratory symptoms Cross-sectional studies Epidemiology |
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