| 盐酸右美托咪定在颅内动脉瘤介入治疗中的麻醉效果 |
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| 引用本文： | 赵贞贞.盐酸右美托咪定在颅内动脉瘤介入治疗中的麻醉效果[J].国际医药卫生导报,2022,28(6):765-768. |
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| 作者姓名： | 赵贞贞 |
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| 作者单位： | 郑州市心血管病医院 郑州市第七人民医院麻醉科，郑州 450000 |
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| 基金项目： | 河南省医学科技攻关项目（201801121） |
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| 摘 要： | 目的 探讨盐酸右美托咪定在颅内动脉瘤介入治疗中的麻醉效果。方法 回顾性分析，选取郑州市心血管病医院2020年1月至2021年8月收治的60例接受介入手术治疗的颅内动脉瘤患者作为研究对象，根据麻醉方案不同将患者分为对照组（30例，接受常规全身麻醉）与研究组（30例，接受右美托咪定全身麻醉）。对照组男17例、女13例，年龄（57.21±6.33）岁；研究组男18例、女12例，年龄（57.38±6.42）岁。对比两组的开眼时间、拔管时间、恢复室停留时间及苏醒时脑电双频指数（BIS），麻醉诱导前（T0）及维持后15 min（T1）、30 min（T2）时的收缩压（SBP）、心率（HR）、平均动脉压（MAP）及麻醉并发症。计量资料组间比较采用独立样本t检验，组内采用配对t检验，计数资料采用χ2检验。结果 T0时，两组颅内动脉瘤患者HR、SBP、MAP比较，差异均无统计学意义（均P>0.05）；T1时，研究组MAP为（99.35±10.62）mmHg（1 mmHg=0.133 kPa），高于对照组（87.45±4.80）mmHg，差异有统计学意义（P<0.05），两组颅内动脉瘤患者HR、SBP比较，差异均无统计学意义（均P>0.05）；T2时，研究组HR、SBP、MAP［（69.52±6.27）次/min、（146.33±5.67）mmHg、（98.12±7.69）mmHg］均高于对照组［（66.43±5.29）次/min、（143.77±3.57）mmHg、（89.38±4.62）mmHg］，差异均有统计学意义（均P<0.05）。研究组开眼时间、恢复室停留时间、拔管时间分别为（16.37±2.03）min、（35.20±10.07）min、（12.28±2.38）min，均短于对照组（24.28±4.95）min、（54.43±12.86）min、（24.20±6.71）min，差异均有统计学意义（均P<0.05）；两组颅内动脉瘤患者苏醒时BIS比较，差异无统计学意义（P>0.05）。两组颅内动脉瘤患者麻醉并发症发生率比较，差异无统计学意义（χ2=0.577，P=0.448）。结论 盐酸右美托咪定在颅内动脉瘤介入手术中的麻醉效果良好确切，患者术中生命体征平稳，术后苏醒质量较高且并发症发生率低。
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| 关 键 词： | 颅内动脉瘤 介入栓塞术 盐酸右美托咪定 苏醒质量 生命体征 |
| 收稿时间： | 2021-11-03 |
Anesthetic effect of dexmedetomidine hydrochloride in interventional treatment for intracranial aneurysms |
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| Zhao Zhenzhen.Anesthetic effect of dexmedetomidine hydrochloride in interventional treatment for intracranial aneurysms[J].International Medicine & Health Guidance News,2022,28(6):765-768. |
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| Authors: | Zhao Zhenzhen |
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| Affiliation: | Department
of Anesthesiology, Zhengzhou Cardiovascular Hospital, Zhengzhou Seventh
People's Hospital, Zhengzhou 450000, China |
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| Abstract: | Objective To investigate the
anesthetic effect of dexmedetomidine hydrochloride in interventional treatment
for intracranial aneurysms. Methods This is a retrospective analysis. A total of 60 patients with
intracranial aneurysms who received interventional treatment in Zhengzhou
Cardiovascular Hospital from January 2020 to August 2021 were selected as the
research objects. According to the different anesthesia schemes, the patients
were divided into a control group (30 cases, receiving conventional general
anesthesia) and a study group (30 cases, receiving general anesthesia with
dexmedetomidine). In the control group, 17 males and 13 females were
(57.21±6.33) years old; in the study group, 18 males and 12 females were
(57.38±6.42) years old. The time of eye opening, extubation time, stay time in
recovery room, bispectral index (BIS) when recovery, and anesthetic
complications were compared between the two groups, as well as systolic blood
pressure (SBP), heart rate (HR), and mean arterial pressure (MAP) before induction
of anesthesia (T0) and 15 min (T1) and 30 min (T2)
after maintenance. Independent sample t test was used for inter-group comparison of the measurement data, paired t test was used for intra-group
comparison of the measurement data, and χ2 test was used for the count data. Results At T0, there were no statistically
significant differences in the HR, SBP, and MAP between the two groups (all P>0.05). At T1, the MAP of
the study group was (99.35±10.62) mmHg (1 mmHg=0.133 kPa), which was higher
than that of the control group (87.45±4.80) mmHg], with a statistically
significant difference (P<0.05);
there were no statistically significant differences in the HR and SBP (both P>0.05). At T2, the HR,
SBP, and MAP of the study group (69.52±6.27) beats /min, (146.33±5.67) mmHg,
and (98.12±7.69) mmHg] were higher than those of the control group
(66.43±5.29) beats /min, (143.77±3.57) mmHg, and (89.38±4.62) mmHg], with
statistically significant differences (all P<0.05).
The time of eye opening, stay time in recovery room, and extubation time in the
study group were (16.37±2.03) min, (35.20±10.07) min, and (12.28±2.38) min,
respectively, which were shorter than those in the control group (24.28±4.95)
min, (54.43±12.86) min, and (24.20±6.71) min], with statistically significant
differences (all P<0.05). There
was no statistically significant difference in the BIS between the two groups
when recovery (P>0.05). There was
no statistically significant difference in the incidence of anesthetic
complications between the two groups (χ2=0.577, P=0.448). Conclusion Dexmedetomidine
hydrochloride has a good anesthetic effect in interventional surgery for
intracranial aneurysms, with stable patients' vital signs during the operation,
high quality of postoperative recovery, and a low incidence of complications. |
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| Keywords: | Intracranial aneurysms Interventional embolization Dexmedetomidine hydrochloride Recovery quality Vital signs |
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