|
|||||
|
|
Pharmacokinetics of chlorthalidone in the elderly after single and multiple doses |
|
| Authors: | D Colussi J P Schoeller A Richard A Sioufi |
| Abstract: | To investigate the discrepancy between the apparent pharmacokinetic disposition of (+)-penicillamine in plasma and urine, the spontaneous degradation of (+)-penicillamine was studied in acidified and non-acidified urine. Degradation was prevented by acidification. The oxidized metabolites were converted to reduced (+)-penicillamine by electrolysis. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |