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Detection of Leptospira DNA in Patients with Aseptic Meningitis by PCR
Authors:Eliete C. Romero, Ana E. C. Billerbeck, Val  ria S. Lando, Eide D. Camargo, Candida C. Souza,   Paulo H. Yasuda
Affiliation:Eliete C. Romero, Ana E. C. Billerbeck, Valéria S. Lando, Eide D. Camargo, Candida C. Souza, and Paulo H. Yasuda
Abstract:Samples of cerebrospinal fluid from 103 patients with aseptic meningitis were tested by PCR for detection of leptospires, and the results were compared with those of the microscopic agglutination test (MAT) and an enzyme-linked immunosorbent assay for detection of immunoglobulin M (ELISA-IgM). Of these samples, 39.80% were positive by PCR and 8.74 and 3.88% were positive by MAT and ELISA-IgM, respectively.
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