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对比剂致急性肾损伤研究进展
引用本文:李鸿杰,唐方明.对比剂致急性肾损伤研究进展[J].心脏杂志,2015,27(2):241-245.
作者姓名:李鸿杰  唐方明
作者单位:广东医学院研究生院,广东湛江,524000;
摘    要:随着冠状动脉介入治疗的快速发展,对比剂的使用越来越广泛,但随之出现的对比剂致急性肾损伤(CI-AKI)目前已成为医院内获得性急性肾衰竭的第3位原因,并且发病率和病死率逐年增加。虽然临床研究者对CI-AKI的发病机制及危险因素研究日趋加深,但由于目前仍缺乏切实有效的防治策略,CI-AKI仍然是重要的临床问题。本文将就CI-AKI的诊断标准、发病机制、危险因素、预防策略及近期研究进展做一综述。

关 键 词:对比剂    急性肾损伤    冠状动脉介入治疗    水化
收稿时间:2014-05-08

Research progress in contrast-induced acute kidney injury
LI Hong-jie;TANG Fang-ming.Research progress in contrast-induced acute kidney injury[J].Chinese Heart Journal,2015,27(2):241-245.
Authors:LI Hong-jie;TANG Fang-ming
Affiliation:1. Graduate School,Guangdong Medical College;2. Department of Internal Medicine,Central Hospital,Guangdong Agriculture Reclamation
Abstract:With the rapid development of coronary artery interventional therapy,contrast media is used more and more widely,but contrast-induced acute kidney injury( CI-AKI) ranks as the third reason for hospital-acquired acute renal failure with a yearly increase in the incidence and mortality rate. Although more studies have been conducted on the pathogenesis and clinical risk of acute renal injury induced by the contrast factors,CI-AKI is still an important clinical problem due to lack of an effective strategy for the prevention of CI-AKI. This article will focus on the recent research progress in the diagnosis,pathogenesis,risk factors,and prevention strategies of CI-AKI.
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