| 新柏式薄层液基细胞学(TCT)联合HPV-DNA分型检测在宫颈癌筛查中的临床价值 |
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| 引用本文： | 姜爱凤,王以新,杨敏京,冯 妍,边连朵.新柏式薄层液基细胞学(TCT)联合HPV-DNA分型检测在宫颈癌筛查中的临床价值[J].现代肿瘤医学,2015,0(20):3015-3017. |
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| 作者姓名： | 姜爱凤 王以新 杨敏京 冯 妍 边连朵 |
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| 作者单位： | 首都医科大学附属北京安贞医院大屯社区卫生服务中心,北京 100029 |
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| 基金项目： | 北京市科技局重点立项课题（编号:20140592） |
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| 摘 要： | 目的:探讨新柏式薄层液基细胞学（TCT）联合HPV-DNA分型检测在宫颈癌筛查中的临床价值。方法:随机选取2011年4月-2014年4月于我院进行宫颈癌筛查的420例患者为研究对象。所有患者均进行TCT及HPV-DNA筛查，并同时进行宫颈组织活检进行最终确认。结果:TCT筛查结果显示:ASCUS（意义不明的不典型鳞状细胞）患者为175例，阳性比例为41.7%。病理组织筛查结果显示:CINⅠ为199例，阳性比例为47.4%。HPV-DNA共检出阳性患者180例，比例42.9%。临床症状越严重，HPV-DNA阳性率越高。TCT联合HPV-DNA筛查结果灵敏度较单独TCT和HPV-DNA筛查结果高，但特异性低，其阳性预测值和阴性预测值都较高，与病理结果筛查结果更为相似。结论:新柏式薄层液基细胞学(TCT)联合HPV-DNA分型检测在宫颈癌筛查中灵敏度高和准确性较高。
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| 关 键 词： | TCT HPV-DNA分型 宫颈癌筛查 临床价值 |
The clinical value of new Parker style TCT combined HPV -DNA genotyping in cervical cancer screening |
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| Jiang Aifeng,Wang Yixin,Yang Minjing,Feng Yan,Bian Lianduo.The clinical value of new Parker style TCT combined HPV -DNA genotyping in cervical cancer screening[J].Journal of Modern Oncology,2015,0(20):3015-3017. |
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| Authors: | Jiang Aifeng Wang Yixin Yang Minjing Feng Yan Bian Lianduo |
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| Affiliation: | Capital Medical University Affiliated An Zhen Hospital of Beijing Datun Community Health Service Center,Beijing 100029,China. |
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| Abstract: | Objective:To explore the clinical value of new type of TCT Parker combined with HPV-DNA typing in detecting cervical cancer screening.Methods:Randomly selected 420 cases of cervical cancer screening patients,all patients underwent TCT and HPV-DNA screening,while cervical biopsy for final confirmation.Results:CT screening showed number of patients with ASCUS 175 cases,the positive ratio 41.7%.Pathology screening showed ≥CINⅠ 199 cases,the positive ratio 47.4%.HPV-DNA positive patients,180 cases were detected,the proportion of 42.9%.The more severe the illness was,the higher the positive rate of HPV-DNA was.Conclusion:The new Parker style TCT combined HPV-DNA genotyping in cervical cancer screening is with high sensitivity and high accuracy. |
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| Keywords: | TCT HPV-DNA typing cervical cancer screening clinical value |
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