Comparison of itraconazole and ketoconazole in the treatment of experimental candidal vaginitis. |
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| Authors: | J D Sobel and G Muller |
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| Abstract: | ![]()
Comparison of itraconazole (R51,211) and ketoconazole in the treatment of experimental candidal vaginitis in rats on schedules of 3 and 5 days revealed significantly superior results with itraconazole at all dosages (1.0 to 7.5 mg/kg) studied, but was particularly evident at 1.0 and 2.5 mg/kg. A single 25-mg/kg dose of itraconazole was as effective as 5 daily 5-mg/kg doses of itraconazole. |
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