| 乙型肝炎肝硬化并发食管胃底静脉曲张破裂出血患者临床特征及影响因素分析 |
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| 引用本文： | 高慧茹,高会斌,彭昭,王璐,霍小辉. 乙型肝炎肝硬化并发食管胃底静脉曲张破裂出血患者临床特征及影响因素分析[J]. 实用肝脏病杂志, 2021, 24(3): 395-398. DOI: 10.3969/j.issn.1672-5069.2021.03.023 |
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| 作者姓名： | 高慧茹 高会斌 彭昭 王璐 霍小辉 |
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| 作者单位： | 075000 河北省张家口市 河北北方学院附属第一医院内镜室(高慧茹,王璐); 消化内科(高会斌,彭昭); 河北医科大学第一医院消化内科(霍小辉) |
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| 基金项目： | 张家口市医药卫生科技发展计划项目(编号:2018360)。 |
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| 摘 要： | 目的 探讨乙型肝炎肝硬化并发食管胃底静脉曲张破裂出血患者的临床特征及其影响因素.方法 2015年6月～2020年6月我院收治的乙型肝炎肝硬化并发食管胃底静脉曲张破裂出血患者90例和同期乙型肝炎肝硬化未出血患者90例,收集患者临床资料,分析乙型肝炎肝硬化并发食管胃底静脉曲张破裂出血患者的临床特征,并采用多因素Logist...
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| 关 键 词： | 肝硬化 食管胃底静脉曲张破裂出血 临床特征 影响因素 |
| 收稿时间： | 2020-08-18 |
Clinical feature and impacting factors of esophageal and gastric variceal bleeding in patients with hepatitis B-induced liver cirrhosis |
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| Gao Huiru,Gao Huibin,Peng Zhao,et al. Clinical feature and impacting factors of esophageal and gastric variceal bleeding in patients with hepatitis B-induced liver cirrhosis[J]. Journal of Clinical Hepatology, 2021, 24(3): 395-398. DOI: 10.3969/j.issn.1672-5069.2021.03.023 |
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| Authors: | Gao Huiru Gao Huibin Peng Zhao et al |
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| Affiliation: | Department of Gastroenterology, First Affiliated Hospital, Hebei North University,Zhangjiakou 075000,Hebei Province,China |
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| Abstract: | Objective The aim of this study was to explore the clinical feature and impacting factors of esophageal and gastric variceal bleeding in patients with hepatitis B-induced liver cirrhosis(LC).Methods The clinical materials in 90 patients with hepatitis B cirrhosis and esophageal and gastric variceal bleeding and in 90 hepatitis with hepatitis B liver cirrhosis and varices were retrospectively analyzed.The impacting factors of variceal bleeding were analyzed by univariate multivariate Logistic regression.Results The univariate analysis showed that the long course of cirrhosis,history of variceal bleeding,the application of non-steroidal drugs,poor Child-Pugh class,the severity of esophageal varices,the widen diameter of left gastric vein and portal vein,the prolonged PT,ascite and low serum albumin level were significantly different between the two groups(P<0.05);the multivariate Logistic regression analysis showed that the long course of cirrhosis,non-steroidal administration,poor Child-Pugh class,the severity of esophageal varices,the widen diameter of left gastric vein and portal vein,the prolonged PT and ascite were the independent risk factors for esophageal varices bleeding in patients with liver cirrhosis(OR=3.145;3.171;2.190;2.672;2.363;3.142;3.083;3.062,P<0.05),while.the high serum albumin level was a protective factor for varices bleeding(OR=0.288,P<0.05).Conclusion Some factors might lead to the esophageal and gastric varices bleeding in patients with hepatitis B liver cirrhosis,which should be paid more attention to and dealing with promptly in clinical practice. |
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| Keywords: | Liver cirrhosis Esophageal and gastric variceal bleeding Clinical features Risk factors |
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