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| 原发性开角型青光眼患者单侧小梁切除术后对侧眼眼压变化 | |
| 引用本文： | 张倩雯,赵灿,裴力,史伟云,王婷. 原发性开角型青光眼患者单侧小梁切除术后对侧眼眼压变化[J]. 眼科新进展, 2021, 0(9): 848-852. DOI: 10.13389/j.cnki.rao.2021.0177 |
| 作者姓名： | 张倩雯 赵灿 裴力 史伟云 王婷 |
| 作者单位： | 256600 山东省滨州市，滨州医学院（张倩雯）；250021 山东省济南市，山东第一医科大学附属眼科医院 山东第一医科大学（山东省医学科学院） 山东省眼科研究所 山东省眼科学重点实验室-省部共建国家重点实验室培育基地(张倩雯，赵灿，裴力，史伟云，王婷) |
| 摘 要： | 目的 观察原发性开角型青光眼患者单眼行外路小梁切除术后对侧眼眼压变化趋势.方法 回顾性分析2016年12月至2021年1月于我院行单眼外路小梁切除术的37例原发性开角型青光眼患者资料,随访并记录患者术后1d、2d、3d、1周、2周、1个月和3个月对侧未手术眼眼压,与术前基线眼压比较.结果 术后1d、2d、3d及1周、2... |
| 关 键 词： | 原发性开角型青光眼 小梁切除术 对侧眼 眼压 |
Intraocular pressure changes in the contralateral eye after unilateral trabeculectomy for primary open angle glaucoma |
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| ZHANG Qianwen1,' target="_blank" rel="external">2,ZHAO Can2,PEI Li2,SHI Weiyun2,WANG Ting2. Intraocular pressure changes in the contralateral eye after unilateral trabeculectomy for primary open angle glaucoma[J]. Recent Advances in Ophthalmology, 2021, 0(9): 848-852. DOI: 10.13389/j.cnki.rao.2021.0177 | |
| Authors: | ZHANG Qianwen1,' target=" _blank" rel=" external" >2,ZHAO Can2,PEI Li2,SHI Weiyun2,WANG Ting2 |
| Affiliation: | 1.Binzhou Medical University,Binzhou 256600,Shandong Province,China2.Eye Hospital of Shandong First Medical University,State Key Laboratory Cultivation Base,Shandong Provincial Key Laboratory of Ophthalmology,Shandong Eye Institute,Shandong First Medical University & Shandong Academy of Medical Sciences,Jinan 250021,Shandong Province,China |
| Abstract: | Objective To investigate the intraocular pressure (IOP) changes in the unoperated contralateral eye of postoperative patients with primary open-angle glaucoma (POAG) after trabeculectomy.Methods A total of 37 patients with POAG receiving unilateral trabeculectomy in our hospital from December 2016 to January 2021 were recruited for retrospective analyses. Postoperative follow-up was performed at 1 day, 2 days, 3 days, 1 week, 2 weeks, 1 month and 3 months. During these follow-up visits, the IOP of the unoperated contralateral eye was recorded to compare with the preoperative baseline, thus observing the IOP changes. Results The IOP of the contralateral eyes increased from (16.38±4.25) mmHg (1 kPa=7.5 mmHg) preoperatively to (18.11±4.03) mmHg, (18.35±5.29) mmHg, (18.03±5.35) mmHg, (17.21±3.33) mmHg, (17.96±3.82) mmHg, (18.57±4.45) mmHg and (17.27±3.73) mmHg at 1 day, 2 days, 3 days, 1 week, 2 weeks, 1 month and 3 months after trabeculectomy, respectively. The differences were statistically significant (P<0.05). The IOP of the contralateral eyes rose from the postoperative first day and reached the maximum at 1 month ［(3.36±4.56) mmHg］, which was 21% higher than that of baseline. The IOP began to return to the baseline 3 months after trabeculectomy. Correlation analysis revealed that the IOP of the contralateral eyes at each time point postoperatively was not correlated with the age and sex of POAG patients (all P>0.05), while it was positively correlated with baseline IOP (all P<0.05). During the follow-up period, 11 POAG patients had a poorly controlled postoperative contralateral IOP (≥21 mmHg and even though preoperative drugs were medicated) that required surgery or additional IOP-lowering drugs. The contralateral IOP changes were correlated with the time point for medicating IOP-lowering drugs. Except for the first day after trabeculectomy (P=0.31), there was a significant difference in the contralateral IOP change during the other follow-up time points between patients with continuous medication preoperatively and those newly medicated (all P<0.05).Conclusion After unilateral trabeculectomy for POAG, the IOP of the contralateral unoperated eye increases in the early stage and gradually decreases to the preoperative baseline 3 months later. It is necessary to strengthen the IOP monitoring of the unoperated eyes after unilateral trabeculectomy in POAG patients. |
| Keywords: | primary open-angle glaucoma trabeculectomy contralateral eye intraocular pressure |
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