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Infections in international pregnancy study: performance of the optical immunoassay test for detection of group B streptococcus
Authors:Thinkhamrop Jadsada  Limpongsanurak Sompop  Festin Mario R  Daly Sean  Schuchat Anne  Lumbiganon Pisake  Zell Elizabeth  Chipato Tsungai  Win Aye Aye  Perilla Mindy J  Tolosa Jorge E  Whitney Cynthia G
Affiliation:Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Bangkok, Thailand. Jadsada@kku.ac.th
Abstract:We evaluated the Strep B optical immunoassay (OIA; ThermoBiostar, Inc.) for detecting light and heavy group B streptococcus colonization in 1,306 pregnant women. The women were examined at 20 to 32 weeks gestation and were from six countries. Compared to culture, the sensitivity and specificity of OIA were 13.3 and 98.4%, respectively, for light colonization and 41.5 and 97.7%, respectively, for heavy colonization.
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