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URB937, a peripherally restricted inhibitor for fatty acid amide hydrolase,reduces prostaglandin E2‐induced bladder overactivity and hyperactivity of bladder mechano‐afferent nerve fibres in rats
Authors:Naoki Aizawa  Giorgio Gandaglia  Petter Hedlund  Tetsuya Fujimura  Hiroshi Fukuhara  Francesco Montorsi  Yukio Homma  Yasuhiko Igawa
Affiliation:1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, Tokyo, Japan;2. Division of Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy;3. Department of Clinical and Experimental Pharmacology, Lund University, Lund, Sweden;4. Division of Drug Research, Department of Medical and Health Sciences, Link?ping University, Link?ping, Sweden;5. Department of Urology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
Abstract:
Keywords:Afferent  endocannabinoids  prostaglandin E2  Sprague–  Dawley rats  urinary bladder
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