| 不同地域结直肠腺瘤检出率及其高危因素对比分析 |
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| 引用本文： | 王伟强,鹿志军. 不同地域结直肠腺瘤检出率及其高危因素对比分析[J]. 中国肿瘤临床, 2017, 44(21): 1090-1094. DOI: 10.3969/j.issn.1000-8179.2017.21.211 |
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| 作者姓名： | 王伟强 鹿志军 |
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| 作者单位： | ①.重庆市第七人民医院消化内科（重庆市 400054） |
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| 摘 要： | ![]()
目的 比较不同地域结直肠腺瘤（colorectal adenoma，CRA）检出率及高危因素。 方法 选取2013年6月至2016年12月重庆市第七人民医院接受肠镜检查者中的研究对象为地域A组（n=2 182）；选取解放军281医院接受肠镜检查中的研究对象为地域B组（n=1 866）。CRA高危因素包括:①大便潜血阳性；②一级亲属有结直肠癌（colorectal carcinoma，CRC）病史；③以往有肠道腺瘤史；④本人有癌症史；⑤有大便习惯的改变；⑥符合慢性腹泻、慢性便秘、黏液血便、慢性阑尾炎或阑尾切除史、慢性胆囊炎或胆囊切除史任意2项者。符合上述任一一项者即为CRA高危人群。对比分析2组CRA及其高危人群检出率、各高危因素分布情况以及各高危因素下CRA的检出率。 结果 地域A组CRA检出率（15.6%）及高危人群检出率（25.8%）与地域B组（15.2%，25.4%）相比差异均无统计学意义（P > 0.05）。2组高危因素分布由高到低均依次为高危因素⑤、⑥、①、③、②、④。2组相比，地域A组高危因素⑤所占比例（36.4%）显著高于地域B组（30.6%）（χ2=3.900，P=0.048）。地域A组高危因素⑤CRA检出率（57.6%）显著高于地域B组（44.1%）（χ2=6.131，P=0.013）。 结论 重庆市第七人民医院与解放军281医院2个不同地区CRA及其高危人群的检出率无显著性差异，但各危险因素的分布不同，不同地域应根据危险因素的不同进行针对性CRA的筛查。
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| 关 键 词： | 结直肠腺瘤 高危因素 地域 结肠镜 |
| 收稿时间： | 2017-02-24 |
Detection rate of colorectal adenoma and its risk factors in different areas |
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| Weiqiang WANG,Zhijun LU. Detection rate of colorectal adenoma and its risk factors in different areas[J]. Chinese Journal of Clinical Oncology, 2017, 44(21): 1090-1094. DOI: 10.3969/j.issn.1000-8179.2017.21.211 |
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| Authors: | Weiqiang WANG Zhijun LU |
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| Affiliation: | ①.Gastroenterology Department of the 7th People's Hospital of Chongqing, Chongqing 400054, China②.Gastroenterology Department of 281 Hospital of PLA, Qinhuangdao 066100, China |
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| Abstract: | ![]()
Objective:To compare the detection rate of colorectal adenoma (CRA) and its risk factors in different areas. Methods:Pa-tients with CRA from the 7th People's Hospital of Chongqing were designated to area group A (n=2182), and those from the 281 Hospi-tal of PLA in Qinhuangdao were designated to area group B (n=1866). The high risk group was screened on the basis of the following factors:①positive fecal occult blood;②colorectal cancer history of first-degree relatives;③intestinal adenoma history;④can-cer history;⑤change in defecation habit;and⑥history of at least two of the following:chronic diarrhea, chronic constipation, mu-cus and bloody stool, chronic appendicitis or appendix removal, and chronic cholecystitis or gallbladder removal. The detection rate of CRA and the high risk groups, the distribution of risk factors, and the detection rate of CRA in every risk factor in the two groups were compared. Results:The detection rate of CRA (15.6%) and the high risk group (25.8%) in area group A were similar to those in area group B (15.2%, 25.4%) (P>0.05). The distributions of risk factors from high to low in the two groups were⑤,⑥,①,③,②, and④. The distribution of risk factor⑤was higher in area group A (36.4%) than in area group B (30.6%) (χ2=3.900, P=0.048). The detec-tion rate of CRA in area group A (57.6%) with factor⑤was higher than that in area group B (44.1%) (χ2=6.131, P=0.013). Conclusion:The detection rate of CRA and the high risk group in the 7th People's Hospital of Chongqing were similar to those in the 281 Hospital of PLA. By contrast, the distributions of risk factors differ in the two area groups. Therefore, the screening direction of CRA in different areas should be based on the risk factors. |
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| Keywords: | colorectal adenoma risk factor area colonoscopy |
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