Correlation between depression and coronary artery lesion
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摘要: 目的 分析抑郁与冠心病患者冠状动脉病变支数及冠状动脉狭窄程度的相关性。方法 随机选取我院2014年1月~2015年1月初步诊断为冠心病的患者353例，均行汉密尔顿抑郁量表（HAMD）测评，根据测评结果分为抑郁组及非抑郁组，然后行冠状动脉造影检查，分析比较两组患者冠脉病变支数及冠脉狭窄程度。结果 两组患者在冠状动脉病变支数和冠状动脉狭窄程度分布构成比上均存在显著差异（均P<0.01)；抑郁组患者3支病变及冠脉狭窄c级和d级所占的比例更高，分别为37.0%、36.1%和38.0%，与非抑郁组患者相比，具有显著性差异（均P<0.05）；非抑郁组患者其单支病变、狭窄a级和狭窄b级比例比较，分别为44.6%、31.0%、31.4%，与75岁及以上患者比有统计学差异（均P<0.05）。结论 抑郁患者的冠状动脉病变累及支数较多且狭窄程度较重。Abstract: AIM To examine the correlation between depression and the number of coronary artery lesions and the severity of coronary stenosis in patients with coronary heart disease (CHD). METHODSThree hundred and fifty-three hospitalized patients with preliminary diagnosis of CHD from January 2014 to January 2015 in our hospital were randomly selected and divided into depression group and non-depression group after Hamilton depression rating scale measurement. Coronary angiography examination was performed in all patients and the number of coronary artery lesions and severity of coronary stenosis were compared between groups. RESULTSThe distribution constituent ratio of the lesion vessel number and the coronary artery stenosis degree was significantly different between groups (both P<0.01). The proportion of grade C and grade D and triple vessel lesions in depression group was significantly higher (36.1%, 38.0% and 37.0%) than those in non-depression group (all P<0.05). The proportion of single vessel lesion and grade A and grade B in non-depression group was significantly higher (44.6%, 31.0% and 31.4%) than those in depression group (all P<0.05). CONCLUSIONThe number of coronary artery lesions is higher and coronary stenosis is more severe in CHD patients with depression.
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期刊类型引用(4)
1. 宋亚光，闫文菊，姚娜，张焕轶，尹鲁骅，周庆秋，孙康. 急性冠脉综合征患者抑郁程度与冠脉狭窄及内皮功能障碍的关系. 山东第一医科大学(山东省医学科学院)学报. 2022(06): 427-434 . 
百度学术
2. 秦利强，杜超，袁亚琴，江平，王立君，刘莉莉. 急性冠脉综合征AVR导联变化类型与焦虑、抑郁的相关性研究. 河北医药. 2021(12): 1858-1861 . 百度学术
3. 王信淳，洪牮，许迪. 抑郁合并冠心病的研究现状. 实用老年医学. 2018(06): 591-593 . 百度学术
4. 辛若丹，李文森，管考华，赵学忠. 焦虑抑郁障碍与冠心病的相关性. 中国老年学杂志. 2017(06): 1556-1559 . 百度学术
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