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徐州不同人群尘螨过敏调查
引用本文:邢道荣,温廷桓. 徐州不同人群尘螨过敏调查[J]. 中国寄生虫学与寄生虫病杂志, 2004, 22(5): 287-289
作者姓名:邢道荣  温廷桓
作者单位:1. 徐州医学院寄生虫学教研室,徐州,221002
2. 复旦大学上海医学院,上海,200032
摘    要:目的 调查徐州市人群包括健康人群和临床上过敏患者对尘螨的反应性。 方法 用尘螨变应原皮肤点刺试验(SPT),并以组胺当量标准检测健康人群及临床门诊有关各科过敏患者的尘螨反应率和反应强度。 结果 健康人群在托幼儿和在校学生222人,弱阳性(+)34人(15.3%),各年龄段间无显著性差异,但女性18.6%(22/118),高于男性11.5(12/104,P<0.05),尤以女幼儿和小学女生的SPT反应率高于中学和大学生。检测临床儿科、耳鼻喉科、呼吸内科、皮肤科过敏患者515例,阳性424例(82.3%)。患者各年龄段及男女性别之间的阳性率差异无显著性(P>0.05)。尘螨SPT强阳性者 (≥ + + + )依次为儿科68.6%,耳鼻喉科63.5%,呼吸内科41.9%,皮肤科25.7%(P<0.01)。强阳性(+ + + )在不同年龄段变化不大 ,特强应答 (+ + + + )在10岁以下低年龄段最高,随着年龄增大而逐渐下降。 结论 徐州地区健康人群尘螨SPT阳性反应率为15.3%,呈弱阳性,过敏患者为82.3%,其中47.9%为强阳性和特强阳性

关 键 词:螨性过敏  粉尘螨  变应原  皮肤点刺试验  徐州
文章编号:1000-7423(2004)-05-0287-03
修稿时间:2003-11-20

Prevalence of Anaphylaxis to Dust Mite in Human Population in Xuzhou
XING Dao rong,WEN Ting huan. Prevalence of Anaphylaxis to Dust Mite in Human Population in Xuzhou[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2004, 22(5): 287-289
Authors:XING Dao rong  WEN Ting huan
Affiliation:Department of Parasitology, Xuzhou Medical College, Xuzhou 221002, China.
Abstract:OBJECTIVE: To study the prevalence of anaphylaxis to dust mite in normal individuals and patients with different allergic disorders in Xuzhou. METHODS: By skin prick test (SPT) with Dermatophagoides farinae allergen extract, the prevalence of the normal individuals and OPD patients visiting hospital with allergic symptoms were examined for hypersensitivity to mite. Histamine equivalent criteria were used to evaluate the reactivity rate and the strength of skin response. Results 34 (15.3%) out of 222 pupils and students of different age groups from different levels of schools regarded as the normal population showed positive reaction to the mite allergen with usually only very weak response(+). There were no significant differences between the different age groups (P > 0.05), but it was different between 18.6% (22/118) in females and 11.5% (12/104) in males (P < 0.05). Also the reactivity rate of younger female pupils was higher than that of older ones. Among 515 cases from the OPD patients with allergic symptoms from pediatrics, ENT, respiratory and dermatology departments, 424 (82.3%) were positive with different grades of skin reaction. The rate of strong reactivity (> or = + + +) was 68.6% in allergic children, 63.5% in patients with allergic rhinitis, 41.9% in patients of respiratory department and 25.7% in patients with dermatitis. The allergic children of < or =10 years old showed highest rate of very strong reactivity (+ + + +), the rates declined along with the growing age. CONCLUSION: In Xuzhou area the SPT reactivity rate to dust mite for normal individuals was 15.3% with only weak response; while for allergic patients it was 82.3%, 47.9% of them showed strong and very strong responses.
Keywords:Anaphylaxis  Dermatophagoides farinae  Allergen  Skin prick test  Xuzhou  
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