Lack of Utility of Specific Immunoglobulin G Antibody Avidity for Serodiagnosis of Reactivated Toxoplasmosis in Immunocompromised Patients |
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| Authors: | B n dicte Mechain, Yves Jean-Fran ois Garin, Florence Robert-Gangneux, Jean Dupouy-Camet, Francis Derouin |
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| Affiliation: | Bénédicte Mechain, Yves Jean-François Garin, Florence Robert-Gangneux, Jean Dupouy-Camet, and Francis Derouin |
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| Abstract: | The avidities of Toxoplasma-specific immunoglobulin G serum antibodies were measured in immunocompromised patients presenting with cerebral or extracerebral toxoplasmosis and/or serological reactivation. Since avidity remained high and stable in 39 of 40 patients with toxoplasmosis and 27 of 28 patients with serological reactivation, we conclude that this test cannot help diagnose toxoplasmosis in these patients. |
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