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Herpes simplex virus infection of human T-cell subpopulations. |
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| Authors: | S M Hammer W P Carney V R Iacoviello B R Lowe M S Hirsch |
| Abstract: | The ability of herpes simplex virus type 1 to productively infect human T-cell subpopulations was examined. Unstimulated helper/inducer (T4+) and cytotoxic/suppressor (T8+) lymphocytes limited herpes simplex virus replication as effectively as unseparated peripheral blood T cells (T3+). Phytohemagglutinin stimulation before infection resulted in equivalently productive herpes simplex virus infections in the three cell fractions. |
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