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| 群体感应抑制剂溴化呋喃酮对牙龈卟啉单胞菌生物膜形成影响的研究 | |
| 引用本文： | Zhang L,Wang S,Zhou X,Xui Y. 群体感应抑制剂溴化呋喃酮对牙龈卟啉单胞菌生物膜形成影响的研究[J]. 华西口腔医学杂志, 2011, 29(5): 469-472. DOI: 10.3969/j.issn.1000-1182.2011.05.005 |
| 作者姓名： | Zhang L Wang S Zhou X Xui Y |
| 作者单位： | 1.口腔疾病研究国家重点实验室, 四川大学, 成都610041; 2.四川大学化学学院, 成都610064;3.四川大学华西口腔医院牙周科, 成都610041 |
| 基金项目： | 国家自然科学基金资助项目(30872872) |
| 摘 要： | 目的 研究群体感应抑制剂溴化呋喃酮对牙龈卟啉单胞菌生物膜形成的影响.方法 采用二倍稀释法,确定溴化呋喃酮对牙龈卟啉单胞菌的最低抑菌浓度(MIC).含无水乙醇的牙龈卟啉单胞菌菌悬液作为阴性对照组,牙龈卟啉单胞菌菌悬液为空白对照组,通过光密度值测定和扫描电镜观察,研究1/4M1C、1/2MIC、MIC、2MIC等不同浓度溴... |
| 关 键 词： | 牙龈卟啉单胞菌 生物膜 溴化呋喃酮 |
| 收稿时间： | 2011-10-25 |
| 修稿时间： | 2011-10-25 |
Quorum sensing inhibitor brominated furanone affects Porphyromonas gingivalis biofilm formation |
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| Zhang Liping,Wang Shuang,Zhou Xiangge,Xui Yi. Quorum sensing inhibitor brominated furanone affects Porphyromonas gingivalis biofilm formation[J]. West China journal of stomatology, 2011, 29(5): 469-472. DOI: 10.3969/j.issn.1000-1182.2011.05.005 | |
| Authors: | Zhang Liping Wang Shuang Zhou Xiangge Xui Yi |
| Affiliation: | 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China; 2. College of Chemistry, Sichuan University, Chengdu 610064, China; 3. Dept. of Periodontology, West China School of Stomatology, Sichuan University, Chengdu 610041, China |
| Abstract: | Objective To study the influence of the quorum sensing inhibitor brominated furanone on Porphyromo-nas gingivalis(P.gingivalis) biofilm formation.Methods Doubling dilution method was used to determine the minimal inhibition concentration(MIC) of brominated furanone on P.gingivalis.Absolute ethyl alcohol added in P.gingivalis bacterial suspension was used as the negative control,while P.gingivalis bacterial suspension as blank control.The influences of 1/4MIC,1/2MIC,MIC,2MIC of brominated furanone on P.gingi... |
| Keywords: | Porphyromonas gingivalis biofilm brominated furanone |
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