Penetration of clindamycin, cefoxitin, and metronidazole into pelvic peritoneal fluid of women undergoing diagnostic laparoscopy. |
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| Authors: | S A Berger M Kupferminc J B Lessing A Gorea I Gull M R Peyser |
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| Affiliation: | Department of Microbiology, Tel-Aviv Medical Center, Israel. |
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| Abstract: | A single dose of clindamycin, cefoxitin, or metronidazole was administered to each of 30 women. The mean concentration of cefoxitin in pelvic fluid at 1 h exceeded those of the other two drugs (P less than 0.007). Cefoxitin concentrations were inferior to those of the other drugs when compared with the published MIC for 90% of Bacteroides fragilis strains. |
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