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| 胸腔注入尿激酶治疗结核性胸膜炎并积液分隔疗效评价 | |
| 引用本文： | 陈蕾,赵庆蓉,陈洪德,罗小英,陈黎,任铭香. 胸腔注入尿激酶治疗结核性胸膜炎并积液分隔疗效评价[J]. 现代临床医学, 2008, 34(6): 425-426 |
| 作者姓名： | 陈蕾 赵庆蓉 陈洪德 罗小英 陈黎 任铭香 |
| 作者单位： | 成都市第十人民医院,四川,成都,610061;成都市第十人民医院,四川,成都,610061;成都市第十人民医院,四川,成都,610061;成都市第十人民医院,四川,成都,610061;成都市第十人民医院,四川,成都,610061;成都市第十人民医院,四川,成都,610061 |
| 摘 要： | 目的：探讨尿激酶胸腔注入治疗结核性胸膜炎并积液分隔的疗效。方法：确诊的结核性胸膜炎并积液分隔53例，随机分为2组，治疗组27例，对照组26例。穿刺引流尽胸腔积液后，治疗组胸腔注入尿激酶20万U＋NS40mL，对照组胸腔注入玻璃酸酶1500U＋NS40mL。3～5d后再次胸腔穿刺引流尽胸腔积液，观察2组用药前后积液范围、积液深度、用药后引流量及毒副反应。结果：治疗组积液范围减少的有效率59．26％，较对照组30．77％有显著性差异（P〈0．05）。引流量：治疗组有效率77．78％，较对照组30．77％差异有显著性（P〈0．01）。结论：尿激酶胸腔注入治疗结核性胸膜炎并积液分隔是一种简便、有效、较为安全的方法。 |
| 关 键 词： | 尿激酶 玻璃酸酶 结核性胸膜炎 |
Clinical Effect Evaluation of Loculated Tuberculous Pleurisy Treated with Intrapleural Urokinase |
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| CHEN Lei,ZHAO Qin-tong,CHEN Hong-de,LUO Xiao-ying,CHEN Li and BEN Ming-xiang. Clinical Effect Evaluation of Loculated Tuberculous Pleurisy Treated with Intrapleural Urokinase[J]. Journal of Modern Clinical Medicine, 2008, 34(6): 425-426 | |
| Authors: | CHEN Lei ZHAO Qin-tong CHEN Hong-de LUO Xiao-ying CHEN Li BEN Ming-xiang |
| Abstract: | Objective:To explore the role of intrapleural injection of urokinase(UK) for patient with loculated tuberculous pleurisy(TP).Methods: 53 patients with loculated TP were divided into 2 groups randomly,UK(n=27) or hyaluronidase(HA,n=26) plus NS 40ml were injected into the pleural cavity. Results:The therapecutic effect of UK group was better than HA group(P<0.05).As comparing the drainage volume of fluid UK group was significantly better than HA group(P<0.01).Conclusion:Intrapleural injection of UK is the effective and sofe method for the treatment of loculated TP. |
| Keywords: | urokinase hyaluronidase tuberculous pleurisy |
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