Characterization of human adenoid cells using surface and functional markers for lymphocyte subpopulations. |
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| Authors: | B Rynnel-Dag , E M ller, E Waterfield |
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| Affiliation: | B Rynnel-Dagöö, E Möller, and E Waterfield |
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| Abstract: | ![]()
Adenoid lymphocytes from children undergoing adenoidectomy were compared with blood cells from the same children using techniques for identifying T cells and B cells. A high proportion of adenoid lymphocytes were immunoglobulin positive cells. Of these only a minor fraction carried receptors for the Fc part of IgG. Adenoid B lymphocytes respond poorly if at all to polyclonal B-cell activators, such as LPS or PPD, which show a different reactivity compared to human splenic cells. The response to anti B2-microglobulin was also different; blood cells responded better than adenoid cells. Thus distinct subpopulations of B lymphocytes reside in different lymphoid organs. The adenoid lymphocyte reactivity might reflect their function in the defence mechanism against infections. |
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