| 针刺治疗血管性痴呆的临床疗效及对超氧化物歧化酶,脂 … |
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| 引用本文： | 赖新生,莫飞智. 针刺治疗血管性痴呆的临床疗效及对超氧化物歧化酶,脂 …[J]. 中国中西医结合杂志, 1998, 18(11): 648-651 |
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| 作者姓名： | 赖新生 莫飞智 |
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| 作者单位： | 广州中医药大学针灸研究所 |
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| 基金项目： | 广东省自然科学基金资助课题!(No .96 0 5 48) |
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| 摘 要： | 目的：观察电针、针刺治疗血管性痴呆（ＶａＤ）的疗效及其对超氧化物歧化酶（ＳＯＤ）、脂质过氧化物（ＬＰＯ）、一氧化氮（ＮＯ）的影响。方法：将４６例血管性痴呆患者按痴呆程度随机分为电针组和针刺组，治疗前后分别进行张氏痴呆修复改量表（ＨＤＳ）、社会活动功能调查表（ＦＡＱ）、神经功能缺损评分对比分析，并检测了ＳＯＤ、ＬＰＯ、ＮＯ的含量，结果：治疗后电针组ＨＤＳ增高、ＦＡＱ增低、ＳＯＤ上升，ＬＰＯ和ＮＯ下降
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| 关 键 词： | 血管性痴呆 针灸疗法 电针 SOD 脂质过氧化物 |
Observation of Clinical Effect of Acupuncture on Vascular Dementia and Its Influence on Superoxide Dismutase, Lipid Peroxide and Nitric Oxide |
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| Lai Xinsheng,Mo Feizhi,Jiang Ganghui,et al Institute of Acupuncture,Guangzhou University of TCM,Guangzhou. Observation of Clinical Effect of Acupuncture on Vascular Dementia and Its Influence on Superoxide Dismutase, Lipid Peroxide and Nitric Oxide[J]. Chinese journal of integrated traditional and Western medicine, 1998, 18(11): 648-651 |
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| Authors: | Lai Xinsheng Mo Feizhi Jiang Ganghui et al Institute of Acupuncture Guangzhou University of TCM Guangzhou |
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| Affiliation: | Institute of Acupuncture, Guangzhou University of TCM, Guangzhou 510407. |
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| Abstract: | Objective: To observe the clinical effect of electroacupuncture and acupuncture on vascular dementia (VaD) and the influence on superoxide dismutase (SOD), lipid peroxide (LPO) and nitric oxide (NO) levels. Methods: Forty six cases of VaD were randomly divided into two groups, the electroacupuncture group (EA group) and the acupuncture group (AP group). Assessment of Hasgawa's dementia scale (HDS), functional activities questionnaire (FAQ) and neurologic deficit scoring were done before and after treatment, and the changes on SOD, LPO and NO levels were observed. Results: After treatment, in the EA group, the HDS elevated, the FAQ lowered, SOD increased and LPO and NO decreased significantly, as compared with before treatment, P<0 01. But these parameters were not changed significantly in the AP group after treatment. The clinical symptoms were improved in both groups, but the reduction on neurologic deficit score was not significant. The total effective rate of the EA group was higher than that of the AP group. Conclusion: The immediate effect of electroacupuncture was superior to that of acupuncture, suggesting that the electroacupuncture was more effective in promoting the intelligence recovery than acupuncture. |
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| Keywords: | vascular dementia acupuncture electroacupuncture superoxide dismutase lipid peroxide nitric oxide |
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