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高频彩色多普勒超声鉴别乳腺良恶性肿瘤:基于其灰阶声像及血流特征性分析
引用本文:刘海燕,郑慧.高频彩色多普勒超声鉴别乳腺良恶性肿瘤:基于其灰阶声像及血流特征性分析[J].中华全科医学,2019,17(9):1551-1553.
作者姓名:刘海燕  郑慧
作者单位:1. 滁州市第一人民医院超声科, 安徽 滁州 239000;
基金项目:安徽省公益性研究联动计划项目(1604f0804027)
摘    要:目的 探讨高频彩色多普勒超声在良性与恶性乳腺肿瘤的灰阶声像及血流特征性分析。 方法 回顾性分析滁州市第一人民医院2016年11月—2018年5月行高频彩色多普勒超声检查的60例乳腺肿瘤患者,依据其术后病理检查结果,分为恶性组30例和良性组30例。对2组乳腺肿瘤的超声灰阶声像特征(肿瘤形态、边界、有无沙砾样钙化、纵/横比、后方回声),以及血流分级与频谱特征进行对比分析,以探讨高频彩色多普勒超声在乳腺肿瘤中的鉴别诊断价值。 结果 ①与良性组相比,恶性组的以下超声灰阶声像特征更为显著:肿瘤形态不规则(25/30 vs. 3/30)、边缘呈“毛刺”或“蟹足样”改变(23/30 vs. 5/30)、沙砾样改变(16/30 vs. 4/30)、纵/横比≥1(13/30 vs. 1/30)、后方回声衰减(11/30 vs. 2/30)等,上述差异均有统计学意义(均P<0.05);②与良性组相比,恶性组以下的血流特征更为显著:血流分布Ⅱ、Ⅲ级(26/30 vs. 4/30)、能测出血流频谱(27/30 vs. 10/30)、血流峰值流速≥20 cm/s(18/30 vs. 2/30)、血流阻力指数≥0.7(25/30 vs. 2/30),上述差异均有统计学意义(均P<0.05)。 结论 高频彩色多普勒超声在良性及恶性乳腺肿瘤中的灰阶声像及血流特征方面,表现差异显著,有较高的鉴别诊断价值。 

关 键 词:高频彩色多普勒超声    乳腺肿瘤    灰阶声像    血流频谱
收稿时间:2018-12-15

High frequency color doppler ultrasound in differentiating benign and malignant breast tumors: analysis based on gray scale ultrasound and blood flow characteristics
Affiliation:Department of Ultrasound, Chuzhou First People's Hospital, Chuzhou, Anhui 239000, China
Abstract:Objective To investigate the characteristics of gray scale ultrasonography and blood flow in benign and malignant breast tumors by high frequency color Doppler ultrasound. Methods A retrospective analysis was made on 60 patients with breast tumors who underwent high frequency color Doppler ultrasonography from November 2016 to May 2018. According to the results of pathological examination, they were divided into malignant group (30 cases) and benign group (30 cases). In order to explore the value of high frequency color Doppler ultrasonography in the differential diagnosis of breast tumors, the gray scale ultrasonographic features of breast tumors (tumor shape, boundary, gravel calcification, longitudinal/transverse ratio, posterior echo) and blood flow grading and spectrum characteristics were compared and analyzed. Results ①Compared with benign group, the following gray scale ultrasonographic features of malignant group were more significant showing irregular shape of tumors (25/30 vs. 3/30), burr-like or crab-foot-like changes at the edge (23/30 vs. 5/30), gravel-like changes (16/30 vs. 4/30), longitudinal/transverse ratio >1(13/30 vs. 1/30), posterior echo attenuation (11/30 vs. 2/30),and the differences were statistically significant (all P<0.05); ②Compared with the benign group, the following blood flow characteristics of malignant group were more significant indicating blood flow distribution II, III (26/30 vs. 4/30), hemorrhagic flow spectrum (27/30 vs. 10/30), peak flow velocity≥20 cm/s (18/30 vs. 2/30), resistance index≥0.7 (25/30 vs. 2/30). The above differences were statistically significant (all P<0.05). Conclusion High-frequency color Doppler ultrasound has distinct manifestations in the gray scale and blood flow characteristics of benign and malignant breast tumors, and has high value in differential diagnosis. 
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