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江苏省不同血糖水平人群心血管病危险因素聚集分析
引用本文:缪伟刚,覃玉,苏健,崔岚,罗鹏飞,杜文聪,周金意.江苏省不同血糖水平人群心血管病危险因素聚集分析[J].中华疾病控制杂志,2019,23(4):436-440.
作者姓名:缪伟刚  覃玉  苏健  崔岚  罗鹏飞  杜文聪  周金意
作者单位:江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009;江苏省疾病预防控制中心慢性非传染病防制所,南京市,210009
基金项目:中央财政转移支付地方卫生计生服务项目
摘    要:  目的  了解江苏省社区不同血糖水平人群主要心血管病危险因素的聚集状况。  方法  2015-2017年在江苏省6个项目点开展以社区人群为基础的筛查项目,共有83 522名35~75岁常住居民纳入本次研究。计算我省中老年人群高血压、肥胖、血脂异常和吸烟4类心血管危险因素的流行率及聚集性,采用非条件Logistic回归分析不同血糖水平与心血管病危险因素聚集风险之间的关系。  结果  江苏省35~75岁居民糖尿病患病率18.9%,其中知晓患病的比例为41.4%。在未知患病人群中,空腹血糖受损和高血糖人群心血管病危险因素聚集的风险分别是正常人群的1.29倍(OR=1.29,95% CI:1.24~1.36,P < 0.001)和1.99倍(OR=1.99,95% CI:1.89~2.08,P < 0.001)。在已知患病人群中,血糖控制率为15.5%,血糖控制与心血管病危险因素聚集并无关联。  结论  高血糖和空腹血糖受损增加成人心血管病危险因素聚集风险,应及时对糖尿病高危人群采取综合干预措施控制血糖。

关 键 词:血糖水平  心血管病危险因素  聚集性
收稿时间:2018-10-20

Different level of fasting blood glucose and cardiovascular risk factors clustering among population of Jiangsu Province
Affiliation:Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
Abstract:  Objective  To analyze the clustering of major cardiovascular risk factors among population with different level of fasting blood glucose (FBG) in Jiangsu provincial communities.  Methods  A population-based screening project was conducted during 2015-2017, with 83 522 residents aged 35-75 years from 6 areas included in the study. Prevalence and the clustering of four cardiovascular risk factors (hypertension, obesity, dyslipidemia and smoking) were analyzed. Binary Logistic regression analysis was performed to explore the relationship between FBG and cardiovascular risk factor clustering.  Results  The prevalence of diabetes was 18.9% among adults aged 35-75 years in Jiangsu province, and 41.4% of them were aware of their disease. Among undiagnosed population, the odd ratios (OR) of cardiovascular risk factors clustering in impaired fasting glucose (IFG) and hyperglycemia group was 1.29 (OR=1.29, 95% CI: 1.24-1.36, P < 0.001) and 1.99 (OR=1.99, 95% CI: 1.89-2.08, P < 0.001), compared with normal FBG group. The control rate of FBG was 15.5% among diagnosed cases. There was no difference in the risk clustering between diabetes patient with and without control of FBG.  Conclusions  Hyperglycemia and IFG increase the risk of cardiovascular risk factor clustering. Comprehensive interventions should be served as an important role to keep blood glucose at a normal level in high-risk population.
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