| 显微镜下肿瘤切除对脑胶质瘤患者预后的影响 |
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| 引用本文： | 叶诚,毛捷,吴昊,黄晓飞. 显微镜下肿瘤切除对脑胶质瘤患者预后的影响[J]. 中华全科医学, 2019, 17(9): 1505. DOI: 10.16766/j.cnki.issn.1674-4152.000981 |
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| 作者姓名： | 叶诚 毛捷 吴昊 黄晓飞 |
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| 作者单位： | 1. 安庆市第一人民医院神经外科, 安徽 安庆 246003; |
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| 基金项目： | 安徽省教育厅自然科学重点项目(KJ2015A141) |
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| 摘 要： | 目的 探讨显微镜下肿瘤切除对脑胶质瘤患者预后的影响。 方法 选取2016年1月—2018年5月在安庆市第一人民医院神经外科就诊的51例脑胶质瘤患者为研究对象,依据不同治疗方式,将其分为观察组(显微手术治疗)33例,对照组(常规开颅切除术治疗)18例,回顾性分析患者的临床资料。 结果 观察组术中出血量、手术时间、切口长度及住院时间均少于对照组,差异有统计学意义(均P<0.05)。与术前相比,术后半年2组定向力、记忆力、语言能力、日常生活能力量表(ADL)等评分均明显升高,且观察组高于对照组,差异有统计学意义(均P<0.05)。观察组术后并发症发生率低于对照组,但差异无统计学意义(P>0.05)。观察组术后临床有效率高于对照组、术后半年复发率低于对照组,差异有统计学意义(均P<0.05)。 结论 显微手术用于脑胶质瘤的治疗,严格把握治疗指征,是安全可行的,其不仅创伤小、术后并发症少,且患者认知功能及日常生活能力均较好,临床疗效确切,值得临床推广。
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| 关 键 词： | 脑胶质瘤 显微手术 开颅切除术 认知功能 |
| 收稿时间： | 2019-01-11 |
Clinical effect of microscopic tumor resection on prognosis of glioma patients |
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| Affiliation: | Department of Neurosurgery, Anqing First People's Hospital, Anqing, Anhui 246003, China |
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| Abstract: | Objective To explore the clinical effect of microsurgical tumor resection on the prognosis of patients with glioma. Methods A total of 51 cases of glioma in the Department of Neurosurgery of Anqing First People's Hospital, from January 2016 to May 2018, were selected as the research objects. According to the different treatment methods, they were divided into the observation group (treatment with microsurgery) 33 cases or the control group (treatment with routine craniotomy) 18 cases, and a retrospective analysis was made regarding to their clinical data. Results The bleeding volume, operation time, incision length and hospitalization time in the observation group were less than those in the control group, and the difference was statistically significant (all P<0.05). Compared with those pre-operation, the scores of orientation, memory, language ability and ADL in the two groups increased significantly in half a year after operation, and the scores in the observation group were higher than those in the control group ,and the difference was statistically significant (all P<0.05). The incidence of postoperative complications in the observation group was lower than that in the control group, but there was no significant difference (P>0.05). The effective rate of treatment in the observation group was higher than that in the control group, and the recurrence rate in the first half a year after operation was lower than that in the control group, and the difference was statistically significant (all P<0.05). Conclusion Microsurgery treatment in glioma should strictly grasp the indications of treatment which is safe and feasible, which not only involves less trauma, fewer complications after operation, but also makes patients have better cognitive function and daily living ability. It has a definite clinical effect and is worthy of clinical promotion. |
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