Absence of lipopolysaccharide in the Lyme disease spirochete, Borrelia burgdorferi |
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| Authors: | K Takayama R J Rothenberg A G Barbour |
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| Abstract: | We were unable to demonstrate the presence of the classic enterobacterium-type lipopolysaccharide in the cells of the Lyme disease spirochete, Borrelia burgdorferi B31. This finding was primarily based on chemical analysis and the absence of free lipid A upon mild acid hydrolysis of the appropriate cell extracts. These results do not preclude the possible existence of an unusual lipopolysaccharide-like compound(s) in B. burgdorferi. |
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