| 规范临床用药, 改善母婴结局:美国《预防新生儿早发型B族链球菌病:ACOG委员会共识》解读 |
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| 引用本文： | 王超,赵扬玉.规范临床用药, 改善母婴结局:美国《预防新生儿早发型B族链球菌病:ACOG委员会共识》解读[J].协和医学杂志,2020,11(4):402-407. |
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| 作者姓名： | 王超 赵扬玉 |
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| 作者单位： | 1.北京大学第三医院妇产科, 北京 100191 |
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| 基金项目： | 国家重点研发计划2016YFC1000408 |
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| 摘 要： | B族链球菌(Group B streptococcus, GBS)生殖道定植和母婴传播是导致孕产妇产褥期感染和新生儿感染/死亡的重要原因之一。目前我国尚无统一的GBS筛查策略, 多数医疗机构参考2010年美国疾控中心联合美国妇产科医师协会(the American College of Obstetricians and Gynecologists, ACOG)等制定的《围产期B族链球菌病预防指南》, 有效降低了GBS相关母婴疾病的发生。2020年1月, ACOG发布更新版B族链球菌妊娠期筛查与产时管理共识, 即《预防新生儿早发型B族链球菌病:ACOG委员会共识》, 该共识对GBS筛查策略、筛查注意事项及抗生素预防性用药等内容进行了更新, 本文对相关内容进行详细解读。
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| 关 键 词： | B族链球菌 筛查策略 预防性干预 |
| 收稿时间： | 2020-03-05 |
Standardize Clinical Medication and Improve Maternal and Neonatal Outcomes: Interpretation on Prevention of Group B Streptococcal Early-onset Disease in Newborns: ACOG Committee Opinion,Number 797 |
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| Affiliation: | 1.Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China2.National Clinical Research Center of Obstetrics and Gynecology, Beijing 100191, China |
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| Abstract: | Colonization of Group B streptococcus (GBS) in the reproductive tract and mother-to-child transmission is an important cause of puerperal infection and neonatal infection/death. Currently, there is no unified screening strategy in China, and most medical institutions adopt the guideline of Prevention of perinatal group B streptococcal disease that formulated by the U.S. Centers for Disease Control and Prevention and the American College of Obstetricians and Gynecologists (ACOG) in 2010. The incidence of GBS related diseases has been reduced significantly. In January 2020, ACOG released a new consensus on GBS screening and intrapartum management:Prevention of Group B Streptococcal Early-Onset Disease in Newborns:ACOG Committee Opinion, Number 797, which updated issues such as timing and procedure for preterm GBS screening andintrapartum antibiotic prophylaxis. Here we present a detailed interpretation on the relevant content. |
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