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2015 - 2016年中山市手足口病病原学监测结果分析
引用本文:黄恩妙,师舞阳,姚梓烽. 2015 - 2016年中山市手足口病病原学监测结果分析[J]. 现代预防医学, 2018, 0(10): 1883-1886
作者姓名:黄恩妙  师舞阳  姚梓烽
作者单位:中山市疾病预防控制中心卫生防疫科,广东 中山 528400
摘    要:
目的 了解2015 - 2016年中山市手足口病病原谱及其流行特征,为其防控提供科学的参考依据。方法 2015 - 2016年期间对手足口病哨点医院监测病例的标本开展肠道病毒检测,对其结果进行流行病学分析。结果 检测1 549份标本,共检出1 225份阳性,检出率为79.08%(1 225/1 549);其中其他肠道病毒(PE)阳性率为49.13%(761/1 549),CA16阳性率为15.75%(244/1 549),EV71阳性率为14.01%(217/1 549),混合感染阳性率为0.19%(3/1 549)。2015年以PE为优势流行株(占66.26%,493/744),全年除2月外病原体阳性率均在较高水平波动,7月达到年度最高峰;2016年上半年以CA16为优势流行株,下半年以PE为优势流行株;全年有2个季节高峰,最高峰为4 - 7月,次高峰为11 - 12月。男女间手足口病病毒检出率无统计学差异;病毒核酸检测阳性病例以5岁以下儿童为主。结论 手足口病病原体每年优势毒株不同,季节高峰主要与流行的优势毒株有关,应加强病原学监测,并重点关注5岁以下人群。

关 键 词:手足口病  肠道病毒  病原学

Pathogenic analysis on the surveillance of hand-foot-and-month disease in Zhongshan from 2015 to 2016
HUANG En-miao,SHI Wu-yang,YAO Zi-feng. Pathogenic analysis on the surveillance of hand-foot-and-month disease in Zhongshan from 2015 to 2016[J]. Modern Preventive Medicine, 2018, 0(10): 1883-1886
Authors:HUANG En-miao  SHI Wu-yang  YAO Zi-feng
Affiliation:Zhongshan Center for Disease Control and Prevention, Zhongshan, Guangdong 528400, China
Abstract:
Objective The aim of this study was to understand the epidemiological characteristics of hand-foot-and-month disease(HFMD) in Zhongshan form 2015 to 2016, and provide evidence for the prevention and control. Methods The epidemiological analysis was conducted on the result of pathogenic surveillance of HFMD from 2015 to 2016. Results 1549 tested fecal specimens were collected. The positive cases were 1225 in total, and the positive rate was 79.08% (1225/1549), in which other enteroviruses rate accounted for 49.13% (761/1549), Coxsackie virus A 16 rate accounted for 15.75% (244/1549), Enterovirus 71 rate accounted for 14.01% (217/1549), and mixed infection rate accounted for 0.19% (3/1549). The dominant etiologic strain in 2015 was other enterovirus (66.26%, 493/744). The positive rate of pathogens in the whole year(in addition to February) was fluctuating at a higher level, and the annual peak was reached in July. The dominant etiologic strain was Coxsackie virus A 16 in first half of 2016, and that in second half of 2016 was other enterovirus. There were two season peaks throughout the year. The highest peak was from April to July, and the second peak was from November to December. There was no gender difference in the detection rate of HFMD virus. HFMD virus infection mainly occurred in children under 5. Conclusion The pathogen of HFMD was different each year. The seasonal peak was mainly related to the prevalent strain of the virus. It is important to continue strengthening the etiological monitoring, and to focus on children under the age of 5.
Keywords:Hand-foot-and-month disease  Enterovirus  Etiology
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