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腰椎间盘MR高信号区形态及信号强度纵向追踪
引用本文:崔运能,杨伟超,方晓潮,赵银霞,张晓东. 腰椎间盘MR高信号区形态及信号强度纵向追踪[J]. 南方医科大学学报, 2018, 38(9): 1135. DOI: 10.12122/j.issn.1673-4254.2018.09.19
作者姓名:崔运能  杨伟超  方晓潮  赵银霞  张晓东
摘    要:目的探讨腰痛患者腰椎间盘高信号区(HIZ)病灶形态及信号强度演变规律。方法回顾性分析2009年1月~2017年1月腰椎MR检查发现HIZ病灶、并在至少1.5年后复查的27名腰痛患者资料。由2名放射科医师阅读MR图像,目测判断复查时HIZ病灶形态改变,分为“增大”、“不变”、“缩小”、“消失”。利用ImageJ软件在MR图像上测量初查及复查时HIZ体积及HIZ信号/脑脊液信号(T2/CSF)比值,对比初查及复查体积及信号强度改变。结果初查可见HIZ累及43个椎间盘,复查时病灶增大10个(23.3%),不变22个(51.2%),缩小9个(20.9%),消失2个(4.7%),另可见4个椎间盘出现新的HIZ病灶。ImageJ软件测量显示,初查及复查HIZ体积相比差异无统计学意义(P>0.05),复查的T2/CSF 信号比值较初查高(P<0.05)。结论经过平均3年3月时间观察,腰痛患者椎间盘大部分HIZ病灶形态保持稳定状态,但信号强度增高。


Changes in shape and signal intensity of high intensity zone in lumbar intervertebraldiscs on magnetic resonance images: a longitudinal study
Abstract:Objective To investigate changes over time in the shape and signal intensity of high intensity zone (HIZ) in thelumbar intervertebral discs on magnetic resonance images in patients with low back pain. Methods The imaging data werecollected from 27 patients with low back pain, who underwent lumbar magnetic resonance (MR) imaging examinations thatidentified HIZ lesions and received follow-up MR examinations at least 1.5 years later over the period from January 2009 toJanuary 2017. The initial and follow-up MR T2WI images of the patients were read by two experienced radiologists tocategorize the changes in the shape of the HIZ lesions into enlarged, unchanged, shrunk, and disappeared. The volume andsignal/cerebrospinal fluid signal intensity (T2/CSF) ratio of the HIZ were measured on sagittal MR images using ImageJsoftware. Results Of the 43 HIZ lesions found in the initial examinations, 22 (51.2%) remained unchanged in the follow-upexaminations, 10 (21.3%) were enlarged, 9 (20.9%) shrank, and 2 (23.3%) disappeared. The follow-up examinations revealed 4new HIZ lesions in the intervertebral discs. The volumes of these lesions did not vary significantly in the follow-upexaminations (P=0.653), but the T2/CSF ratio was significantly higher in the follow- up than in the initial examinations (P=0.043). Conclusion After observation for an average of 3 years and 3 months, most of the HIZ lesions in the lumbarintervertebral discs of the patients with low back pain remained stable in shape, but their signal intensity on MR imagesincreased.
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