| 紫外光-核黄素胶原交联疗法治疗真菌性角膜溃疡临床观察 |
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| 引用本文： | 马小倩,刘苏冰,聂晓丽,买志彬,孙红燕,周远沛,曹吉星.紫外光-核黄素胶原交联疗法治疗真菌性角膜溃疡临床观察[J].眼科新进展,2015,0(10):965-967. |
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| 作者姓名： | 马小倩 刘苏冰 聂晓丽 买志彬 孙红燕 周远沛 曹吉星 |
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| 作者单位： | 450016 河南省郑州市，郑州大学第二附属医院、武警河南总队医院、郑州视光眼科医院 |
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| 摘 要： | 目的 探讨紫外光-核黄素胶原交联疗法治疗真菌性角膜溃疡的有效性。方法对２０１４年７月至１２月在郑州视光眼科医院就诊的８例真菌性角膜溃疡患者，在综合药物治疗至少１周以上无效或效果欠佳的情况下给予药物联合紫外光-核黄素胶原交联疗法。用裂隙灯检查患者的角膜变化情况，追踪访问其主观感受，用共聚焦显微镜观察真菌菌丝并检测角膜各层细胞的形态变化。结果 ７例病变深及前中部基质层的患者术后溃疡灶愈合；１例病变深及深基质层者病情未得到有效控制。所有患者未见手术相关并发症。结论 对于综合药物治疗无效或效果欠佳的真菌性角膜溃疡，使用紫外光-核黄素胶原交联疗法治疗有明显临床效果。
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| 关 键 词： | 角膜溃疡 交联疗法 紫外光 核黄素 真菌感染 |
Ultraviolet A-riboflavin corneal collagen cross-linking for fungal corneal ulcer |
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| MA Xiao-Qian,LIU Su-Bing,NIE Xiao-Li,MAI Zhi-Bin,SUN Hong-Yan,ZHOU Yuan-Pei,CAO Ji-Xing.Ultraviolet A-riboflavin corneal collagen cross-linking for fungal corneal ulcer[J].Recent Advances in Ophthalmology,2015,0(10):965-967. |
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| Authors: | MA Xiao-Qian LIU Su-Bing NIE Xiao-Li MAI Zhi-Bin SUN Hong-Yan ZHOU Yuan-Pei CAO Ji-Xing |
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| Affiliation: | Zhenghzhou University , Armed Police Crops Hospital of Henan , Lumi Vision Hospital of Zhengzhou, Zhengzhou 450016 .Henan Province , China |
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| Abstract: | Objective To investigate the efficiency of ultraviolet A-riboflavin corneal collagen cross-linking ( CXL) in treatment of fungal corneal ulcer. Methods Eight patients with fungal corneal in our hospital from July 2014 to December 2014 were treated with CXL combining with medications after poor therapeutic effects of comprehensive therapy with only medications. The corneal status was observed with slit-lamp , the corneal cells were examined with confocal microscopy and patients’ subjective feelings were recorded. Results The conjunctival hyperaemia in 7 patients were relieved. and their ulcers were healed after the operation. I patient with the deep matrix layer infected didn’ t recover after the operation. No postoperative complication was found. Conclusion CXL is effective for fungal corneal ulcer.which can not achieve ideal efficacy with the treatment of medications. |
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| Keywords: | corneal ulcer cross-linking ultraviolet riboflavin fungus |
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