| 北京协和医院1990—2009年住院患者尿道感染常见病原菌及其耐药性 |
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| 引用本文： | 张小江,谢秀丽,孙宏莉,杨启文,王辉,徐英春. 北京协和医院1990—2009年住院患者尿道感染常见病原菌及其耐药性[J]. 协和医学杂志, 2010, 1(1): 87-90 |
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| 作者姓名： | 张小江 谢秀丽 孙宏莉 杨启文 王辉 徐英春 |
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| 作者单位： | 中国医学科学院 北京协和医学院 北京协和医院检验科, 北京 100730 |
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| 摘 要： | 目的 了解住院患者尿道细菌感染常见病原菌及其对抗菌药物的耐药性。 方法 用纸片扩散法对1990-2009年北京协和医院住院患者尿道感染分离的4565株病原菌进行抗菌药物耐药监测。 结果 20年来北京协和医院住院患者尿道感染以大肠埃希菌检出率最高(33%), 其次为粪肠球菌(12%)、屎肠球菌(8%)、凝固酶阴性葡萄球菌(7%)、铜绿假单胞菌(6%)和肺炎克雷伯菌(6%)。2006-2009年产超广谱β-内酰胺酶(extended-spectrum beta-lac-tamases, ESBLs)的大肠埃希菌检出率为60%;大肠埃希菌对亚胺培南、美罗培南和厄他培南均100%敏感, 对环丙沙星和左氧氟沙星的耐药率为77.7%和76.4%。粪肠球菌对呋喃妥因和磷霉素的耐药率均低于10%。 结论 住院患者尿道感染最常见的病原菌是大肠埃希菌, 且细菌耐药性呈增长趋势, 临床上应加强细菌耐药监测。
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| 关 键 词： | 尿道感染 病原菌 细菌耐药性 |
| 收稿时间： | 2010-04-08 |
Pathogens and Antibiotic Resistance of Isolates from Patients with Urinary Tract Infections in Peking Union Medical College Hospital,1990-2009 |
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| ZHANG Xiao-Jiang,XIE Xiu-li,SUN Hong-li,YANG Qi-wen,WANG Hui,XU Ying-chun Laboratory of Clinical Microbiology,Peking Union Medical College Hospital,Chinese Academyof Medical Sciences , Peking Union Medical College,Beijing ,China. Pathogens and Antibiotic Resistance of Isolates from Patients with Urinary Tract Infections in Peking Union Medical College Hospital,1990-2009[J]. Medical Journal of Peking Union Medical College Hospit, 2010, 1(1): 87-90 |
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| Authors: | ZHANG Xiao-Jiang XIE Xiu-li SUN Hong-li YANG Qi-wen WANG Hui XU Ying-chun Laboratory of Clinical Microbiology Peking Union Medical College Hospital Chinese Academyof Medical Sciences & Peking Union Medical College Beijing China |
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| Affiliation: | Laboratory of Clinical Microbiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China |
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| Abstract: | Objective To identify the common pathogens of urinary tract infections and the potential existence of drug resistance. Methods A total of 4565 clinical isolates from patients with urinary tract infections were collected in Peking Union Medical College Hospital from 1990 to 2009. Antimicrobial susceptibility was detected by disk diffusion method. Results The most common pathogen identified was E. coli (33%),followed by Enterococcus faecalis (12%),Enterococcus faecium (8%),coagulase negative staphylococcus (7... |
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| Keywords: | urinary tract infection pathogenic bacterium bacterial resistance |
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