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| Corvis ST评估不同程度近视成年患者的眼角膜生物力学参数及其与年龄、近视程度的相关性 | |
| 引用本文： | 李雪,牛勇毅,罗超,刘志慧,陆强.Corvis ST评估不同程度近视成年患者的眼角膜生物力学参数及其与年龄、近视程度的相关性[J].眼科新进展,2023,0(4):318-322. |
| 作者姓名： | 李雪 牛勇毅 罗超 刘志慧 陆强 |
| 作者单位： | 528000 广东省佛山市，佛山市第二人民医院眼科，佛山市眼科研究所（李雪，罗超，刘志慧，陆强）；510080 广东省广州市，广东省人民医院眼科，广东省眼科研究所，广东省医学科学院（牛勇毅） |
| 摘 要： | 目的 应用Corvis ST评估不同近视程度成年患者的角膜生物力学及及与年龄、近视程度的相关性。方法 横断面研究。收集2021年1月至8月在佛山市第二人民医院眼科门诊就诊的拟行屈光手术的近视患者101例(101眼，右眼)。根据等效球镜屈光度(SE)分为轻度近视组(SE>-3.00 D)组(12眼)、中度近视组(-6.00 D |
| 关 键 词： | 近视 超高度近视 角膜生物力学 |
Evaluation on correction between corneal biomechanical parameters of adult patients with different degrees of myopia and age,severity of myopia by corneal visualization scheimpflug technology |
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| LI Xue,NIU Yongyi,LUO Chao,LIU Zhihui,LU Qiang.Evaluation on correction between corneal biomechanical parameters of adult patients with different degrees of myopia and age,severity of myopia by corneal visualization scheimpflug technology[J].Recent Advances in Ophthalmology,2023,0(4):318-322. | |
| Authors: | LI Xue NIU Yongyi LUO Chao LIU Zhihui LU Qiang |
| Affiliation: | 1.Department of Ophthalmology,Foshan Eye Institute,The Second People’s Hospital of Foshan,Foshan 528000,Guangdong Province，China2.Department of Ophthalmology,Guangdong Eye Institute,Guangdong Provincial People’s Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080，Guangdong Province，China |
| Abstract: | Objective To evaluate the corneal biomechanical parameters of patients with varying degrees of myopia and their relation with the age of patients and severity of myopia using corneal visualization scheimpflug technology (Corvis ST). Methods In this cross-sectional study, 101 right eyes of 101 patients who visited the Ophthalmology Clinic, Foshan Second People’s Hospital and planned to undergo refractive surgery from January to August 2021 were included. Based on the spherical equivalent (SE), patients were divided into the mild myopia group (SE >-3.00 D) (12 eyes), medium myopia group (-6.00 D < SE ≤-3.00 D) (39 eyes), high myopia group (-10.00 D < SE ≤ -6.00 D) (39 eyes), and ultrahigh myopia group (SE ≤-10.00 D) (11 eyes). The corneal biomechanical parameters of patients in all groups were measured and compared by IOLMaster 700, Pentacam and Corvis ST. With central corneal thickness (CCT) and biomechanically corrected intraocular pressure (bIOP) as controlled variables, the relationship between age, SE and corneal biomechanical parameters was analyzed using partial correlation analysis. The stepwise regression analysis was performed separately to explore the impact of age on various biomechanical parameters after the single-factor screening. Results There were significant differences in the overall comparison and pairwise comparison of axial length (AL) and peak distance at the highest concavity (HC-PD) (all P<0.05). There were significant differences in the overall comparison of SE, highest concavity radius (HCR), deformation amplitude at the highest concavity (HC-DA), stiffness parameter applanation 1 (SP-A1), integrated radius (IR), and deformation amplitude ratio (DA Ratio) at 2 mm (all P<0.05). There were significant differences in the SE between the mild myopia group and high myopia group, mild myopia group and ultrahigh myopia group, medium myopia group and high myopia group, as well as medium myopia group and ultrahigh myopia group (all P<0.05), and no significant difference in the SE between the mild myopia group and medium myopia group, high myopia group and ultrahigh myopia group (Pmild-medium=0.050 and Phigh-ultrahigh=0.075). The HCR of patients in the high myopia group was significantly higher than that in the ultrahigh myopia group (P=0.044), and other pairwise comparisons of HCR had no significant difference (all P>0.05). The HC-DA of patients in the mild myopia group was significantly lower than that in the medium myopia group, high myopia group and ultrahigh myopia group (Pmild-medium=0.002, Pmild-high=0.004, and Pmild-ultrahigh=0.016), and other pairwise comparisons of HC-DA had no significant difference (all P>0.05). The SP-A1 of patients in the mild myopia group was significantly higher than that in the medium myopia group, high myopia group and ultrahigh myopia group (Pmild-medium=0.016, Pmild-high=0.002, and Pmild-ultrahigh=0.003), and other pairwise comparisons of SP-A1 had no significant difference (all P>0.05). The IR of patients in the mild myopia group was significantly lower than that in the medium myopia group and ultrahigh myopia group (Pmild-medium=0.021 and Pmild-ultrahigh=0.013), and other pairwise comparisons of IR had no significant difference (all P>0.05). The DA Ratio at 2 mm of patients in the mild myopia group was significantly lower than that in the medium myopia group (P=0.038), and other pairwise comparisons had no significant difference (all P>0.05). Conclusion DA Ratio at 2 mm and IR well reflect the corneal biomechanical properties of mild myopia patients. HCR is significantly smaller in ultrahigh myopia patients, suggesting that corneal biomechanical properties are weakened, and the cornea is prone to deformation. |
| Keywords: | myopia ultrahigh myopia corneal biomechanics |
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