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颅内动脉瘤的支架辅助弹簧圈栓塞的疗效分析
引用本文:程魁红,赵刚,张锡武,陈状,张建波,江澈,武肖娜,罗高权.颅内动脉瘤的支架辅助弹簧圈栓塞的疗效分析[J].中国临床神经外科杂志,2022,27(8):633-636.
作者姓名:程魁红  赵刚  张锡武  陈状  张建波  江澈  武肖娜  罗高权
作者单位:510515 广州,南方医科大学第一临床医学院(程魁红、赵刚);510010 广州,中国人民解放军南部战区总医院神经外科(程魁红、赵刚、张锡武、陈状、张建波、江澈、武肖娜、罗高权)
摘    要:目的 探讨支架辅助弹簧圈栓塞治疗颅内动脉瘤的有效性和安全性。方法 回顾性分析2019年6~9月支架辅助弹簧圈栓塞治疗的62例颅内动脉瘤的临床资料。结果 所有动脉瘤均成功栓塞,62个动脉瘤共置入支架64枚,其中Neuroform支架3枚,Solitaire支架8枚,LVIS支架10枚,Enterprise支架43枚;2个动脉瘤各置入2枚。术后即刻造影显示Raymond分级Ⅰ级53例(85.48%),Ⅱ级3例(4.84%),Ⅲ级6例(9.68%)。术中发生动脉瘤破裂2例(3.23%),术后发生缺血性事件2例(3.23%)。出院时,改良Rankin量表(mRS)评分0~2分50例(80.65%),3~5分10例,死亡2例。57例临床随访6~32个月,平均19.7个月,未出现动脉瘤再出血或新发梗死;mRS评分0~2分48例(84.21%)分,3~5分9例。30例影像学随访3~24个月,平均9.3个月,1例(3.33%)出现少量瘤颈复发。结论 支架辅助弹簧圈栓塞治疗颅内动脉瘤是可行、安全的,术中需要根据动脉瘤和载瘤动脉的具体情况以及治疗策略决定选取合适的支架。

关 键 词:颅内动脉瘤  血管内栓塞  支架  弹簧圈  疗效

Efficacy and safety of stent-assisted coil embolization for patients with intracranial aneurysm
CHEN Kui-hong,,ZHAO Gang,,ZHANG Xi-wu,CHEN Zhuang,ZHANG Jian-bo,JIANG Che,WU Xiao-na,LUO Gao-quan.Efficacy and safety of stent-assisted coil embolization for patients with intracranial aneurysm[J].Chinese Journal of Clinical Neurosurgery,2022,27(8):633-636.
Authors:CHEN Kui-hong    ZHAO Gang    ZHANG Xi-wu  CHEN Zhuang  ZHANG Jian-bo  JIANG Che  WU Xiao-na  LUO Gao-quan
Affiliation:1. First Clinical School of Medicine, Southern Medical University, Guangzhou 510515, China; 2. Department of Neurosurgery, General Hospital of Southern Theater Command, PLA, Guangzhou 510010, China
Abstract:Objective To analyze the efficacy and safety of stent-assisted coil embolization for the patients with intracranial aneurysm. Methods The clinical data of 62 patients with intracranial aneurysm undergoing stent-assisted coil embolization from June 2019 to September 2019 were retrospectively analyzed. Results All the aneurysms were successfully embolized. A total of 64 stents were implanted in 62 aneurysms, including 3 Neuroform stents, 8 Solitaire stents, 10 LVIS stents, and 43 Enterprise stents; 2 aneurysms were implanted 2 stents each. Immediate postoperative angiography showed Raymond grade Ⅰ in 53 patients (85.48%), grade Ⅱ in 3 (4.84%), and grade Ⅲ in 6 (9.68%). Intraoperative re-bleeding occurred in 2 patients (3.23%), and postoperative ischemic events occurred in 2 patients (3.23%). On discharge, the modified Rankin Scale (mRS) score of 0~2 was achieved in 50 patients (80.65%), score of 3~5 in 10, and 2 patients died. The clinical follow up of 57 patients (range, 6~32 months; average, 19.7 months) showed no aneurysm rebleeding or new infarction; mRS score of 0~2 in 48 patients (84.21%) and score of 3~5 in 9. The imaging follow-up of 30 patients (range, 3~24 months; average, 9.3 months) showed aneurysmal recurrence in 1 patient (3.33%). Conclusions Stent-assisted coil embolization is feasible and safe for the treatment of intracranial aneurysms. During the embolization, the appropriate stent should be selected according to the specific conditions of the aneurysms and parent arteries and the treatment strategies.
Keywords:Intracranial aneurysms  Endovasculuar embolization  Stents  Coil  Efficacy  Safety
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