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肉芽肿性小叶性乳腺炎21例临床病理观察
引用本文:牛多山,徐美林,杨杰,姚丰,夏巧凡. 肉芽肿性小叶性乳腺炎21例临床病理观察[J]. 现代肿瘤医学, 2022, 0(4): 626-629. DOI: 10.3969/j.issn.1672-4992.2022.04.014
作者姓名:牛多山  徐美林  杨杰  姚丰  夏巧凡
作者单位:宣城市人民医院病理科,安徽 宣城 242000
摘    要:目的:探讨肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis,GLM)的临床病理学特征、诊断及鉴别诊断.方法:回顾性分析21例GLM,并复习相关文献.结果:21例患者均为女性,年龄24~49岁,中位年龄31岁,均以单侧乳腺肿块就诊,可伴疼痛、皮肤红肿、破溃等.大体上肿块无包膜,切面呈实性...

关 键 词:肉芽肿性小叶性乳腺炎  临床病理  诊断

Granulomatous lobular mastitis:A clinicopathologic analysis of 21 cases
NIU Duoshan,XU Meilin,YANG Jie,YAO Feng,XIA Qiaofan. Granulomatous lobular mastitis:A clinicopathologic analysis of 21 cases[J]. Journal of Modern Oncology, 2022, 0(4): 626-629. DOI: 10.3969/j.issn.1672-4992.2022.04.014
Authors:NIU Duoshan  XU Meilin  YANG Jie  YAO Feng  XIA Qiaofan
Affiliation:Department of Pathology,Xuancheng People's Hospital,Anhui Xuancheng 242000,China.
Abstract:Objective:To explore the clinicopathologic features,diagnosis and differential diagnosis of granulomatous lobular mastitis(GLM).Methods:21 cases of GLM were analyzed retrospectively and related literature was reviewed.Results:All the 21 patients were female,aged 24~49 years,with a median age of 31 years.All patients visited the clinic with unilateral breast mass,which could be accompanied by pain,skin redness,swelling and ulceration.Grossly,the mass had no envelope,and the section was solid or cystic.The solid area was gray or grayish yellow,with a hard and tough texture.The cystic area was putrid and contains a gray-yellow-gray-brown purulent secretion.Microscopically,it was characterized by centrilobular granulomas inflammation,with neutrophils infiltration and lipid absorption vacuole.The lobular was still preserved usually.The patients were followed up for 3~36 months after operation.2 patients suffered from disease recurrence.Conclusion:GLM is a rare idiopathic breast inflammatory disease with certain clinicopathological characteristics.Clinicians and pathologists should pay attention to it to avoid misdiagnosis and mistreatment.
Keywords:granulonlatous lobular mastitis  clinical and pathological features  diagnosis
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