Azithromycin retards Pseudomonas aeruginosa biofilm formation |
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| Authors: | Gillis Richard J Iglewski Barbara H |
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| Affiliation: | Department of Microbiology and Immunology, Box 672, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. |
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| Abstract: | Using a flow cell biofilm model, we showed that a sub-MIC of azithromycin (AZM) can delay but not inhibit Pseudomonas aeruginosa biofilm formation and results in the development of a stable AZM resistance phenotype. Furthermore, mature biofilms were not affected by AZM. |
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