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Erythema multiforme after orf virus infection
Authors:Angella López‐Cedeño MD  Gustavo Cañedo MD  Nicole Knöpfel MD  Isabel Colmenero MD  Esperanza Pérez‐Pastrana MD  Antonio Torrelo MD
Affiliation:1. Department of Dermatology, Hospital Infantil Universitario Ni?o Jesús, Madrid, Spain;2. Department of Pediatrics, Hospital Infantil Universitario Ni?o Jesús, Madrid, Spain;3. Department of Pathology, Hospital Infantil Universitario Ni?o Jesús, Madrid, Spain;4. Electron Microscopy Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain
Abstract:The case of a 6‐year‐old boy with multiple, target‐shaped lesions and a crusted nodule on his right index finger is presented. Based on clinical findings and the patient's recent contact with sheep and goats, a diagnosis of orf disease associated with erythema multiforme was suspected. Microscopy studies confirmed the presence of parapoxvirus in the primary lesion. Orf‐induced erythema multiforme is a rare complication of orf in children, possibly related to the presence of orf virus DNA in erythema multiforme lesions.
Keywords:erythema multiforme  intracytoplasmic inclusions  Orf disease  parapoxvirus
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