Glomerulonephritis with γ- and β1C-Globulin Deposits Induced in Rats by Mercuric Chloride |
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| Authors: | Jean Bariety, Philippe Druet, Fran ois Laliberte, Catherine Sapin |
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| Affiliation: | Jean Bariety, Philippe Druet, François Laliberte, and Catherine Sapin |
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| Abstract: | Repeated subcutaneous injections of 0.15 or 0.25 mg/100 g of body weight of HgCl2 may induce a membranous glomerulonephritis in rats. This glomerulonephritis with subepithelial deposits is similar, by electron microscopy and immunohistochemistry, to experimental chronic glomerulonephritis caused by immune complexes and to the human membranous glomerulonephritis. |
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