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S3 Guideline for the treatment of psoriasis vulgaris,update – Short version part 1 – Systemic treatment
Authors:Alexander Nast  Lasse Amelunxen  Matthias Augustin  Wolf‐­Henning Boehncke  Corinna Dressler  Matthew Gaskins  Peter Härle  Bernd Hoffstadt  Joachim Klaus  Joachim Koza  Ulrich Mrowietz  Hans‐Michael Ockenfels  Sandra Philipp  Kristian Reich  Thomas Rosenbach  Berthold Rzany  Martin Schlaeger  Gerhard Schmid‐Ott  Michael Sebastian  Ralph von Kiedrowski  Tobias Weberschock
Affiliation:1. Charité ‐ Universit?tsmedizin Berlin, corporate member of Freie Universit?t Berlin, Humboldt‐Universit?t zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology und Allergy, Division of Evidence‐Based Medicine (dEBM);2. Fachklinik Bad Bentheim [Bad Bentheim Specialist Hospital];3. Universit?tsklinikum Hamburg‐Eppendorf, Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen [University Hospital Hamburg‐Eppendorf, Institute for Health Care Research in Dermatology and Nursing];4. Service de Dermatologie et Vénéréologie, H?pitaux Universitaires de Genève [Dermatology and Venereology Service, Geneva University Hospitals];5. Katholisches Klinikum Mainz, Zentrum für Rheumatologische Akutdiagnostik, Klinik für Rheumatologie, Klinische Immunologie und Physikalische Therapie [Catholic Medical Center Mainz, Center for Rheumatological Diagnostics, Department of Rheumatology, ClinicaI Immunology and Physical Therapy];6. Selbsthilfegemeinschaft Haut e. 7. V. [Skin self‐help association];8. Deutscher Psoriasis Bund e. 9. V. [German Psoriasis Society];10. Psoriasis‐Zentrum, Klinik für Dermatologie, Venerologie, AllergologieUniversit?tsklinikum Schleswig‐Holstein, Campus Kiel [Psoriasis Center, Department of Dermatology, Venereology and Allergology, University Hospital Schleswig‐Holstein Kiel campus];11. Haut‐ und Allergieklinik, Klinikum Hanau [Department of Dermatology and Allergology, Hanau Medical Center];12. Charité ‐ Universit?tsmedizin Berlin, corporate member of Freie Universit?t Berlin, Humboldt‐Universit?t zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology und Allergy, Psoriasisstudienzentrum [Psoriasis Study Center];13. Dermatologikum Hamburg [Dermatologikum Hamburg];14. Niedergelassener Dermatologe, Osnabrück [Office‐based Dermatologist, Osnabrück];15. Privatpraxis Rzany & Hund, Berlin [Office‐based Dermatologists Rzany & Hund, Berlin];16. Niedergelassener Dermatologe, Oldenburg [Office‐based Dermatologist, Osnabrück];17. Berolina Klinik, L?hne [Berolina Medical Center, L?hne];18. Niedergelassener Dermatologe, Mahlow [Office‐based Dermatologist, Mahlow];19. Niedergelassener Dermatologe, Selters [Office‐based Dermatologist, Selters];20. Klinik für Dermatologie, Venerologie und Allergologie, Universit?tsklinikum Frankfurt, Frankfurt/Main und Arbeitsgruppe EbM Frankfurt, Institut für Allgemeinmedizin, Goethe‐Universit?t Frankfurt, Frankfurt/Main [Department of Dermatology, Venereology and Allergology, Frankfurt University Hospital, Frankfurt/Main and EbM Frankfurt working group, Institute for General Medicine, Goethe University Frankfurt, Frankfurt/Main]
Abstract:
The German guideline for the treatment of psoriasis vulgaris was updated using GRADE methodology. The guideline is based on a systematic literature review completed on December 1, 2016, and on a formal consensus and approval process. The first section of this short version of the guideline covers systemic treatment options considered relevant by the expert panel and approved in Germany at the time of the consensus conference (acitretin, adalimumab, apremilast, cyclosporine, etanercept, fumaric acid esters, infliximab, methotrexate, secukinumab and ustekinumab). Detailed information is provided on the management and monitoring of the included treatment options.
Keywords:
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