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| 奥曲肽与垂体后叶素治疗肝硬化上消化道出血的效果评价 | |
| 引用本文： | 刘黎明,胡东辉. 奥曲肽与垂体后叶素治疗肝硬化上消化道出血的效果评价[J]. 现代预防医学, 2015, 0(17): 3255-3257 |
| 作者姓名： | 刘黎明 胡东辉 |
| 作者单位： | 湖北省中山医院肝病科，湖北 武汉 430033 |
| 摘 要： | 摘要:目的 研究奥曲肽与垂体后叶素合用在治疗肝硬化上消化道出血中的作用。方法 以某院消化内科2011年3月-2013年12月收治的80例肝硬化上消化道出血患者作为研究对象，根据是否联合使用奥曲肽和垂体后叶素将患者分为实验组和对照组，每组各40例；在一般对症支持治疗的基础上，实验组患者采用奥曲肽与垂体后叶素联合治疗，对照组仅采取奥曲肽治疗，比较2组患者治疗有效率、止血时间、不良反应等指标。结果 实验组40例患者中，38例有效，有效率为95.0%，对照组40例患者中，28例有效，有效率为70.0%，两者差异有统计学意义。实验组平均止血时间为（36.2±10.7）h，对照组平均止血时间为（48.3±11.6）h，两者差异有统计学意义（P＜0.05）。2组患者不良反应发生率差异无统计学意义（P＞0.05）。结论 奥曲肽与垂体后叶素联合使用治疗肝硬化上消化道出血在治疗有效率、止血时间上效果显著，不良反应发生率与单用奥曲肽相比也无明显差异，此方案值得在临床上进一步推广。 |
| 关 键 词： | 关键词:奥曲肽 垂体后叶素 消化道出血 肝硬化 |
Assessment of upper gastrointestinal bleeding of clinical effect assessment by octreotide and hypophysin |
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| LIU Li-ming,HU Dong-hui. Assessment of upper gastrointestinal bleeding of clinical effect assessment by octreotide and hypophysin[J]. Modern Preventive Medicine, 2015, 0(17): 3255-3257 | |
| Authors: | LIU Li-ming HU Dong-hui |
| Affiliation: | Zhongshan Hospital of Hubei Province, Wuhan, Hubei 430033, China |
| Abstract: | Abstract: Objective To assess the effect of octreotide and hypophysin in treatment of upper gastrointestinal bleeding in cases with liver cirrhosis. Methods A total of 80 cases with liver cirrhosis upper gastrointestinal bleeding were collected as the research objectives from March 2011 to December 2013. According to whether using the combination of the octreotide and pituitrin, we divided the patients into the experimental group and the control group, 40 cases in each group. On the basis of general support therapy, the experimental group was treated by Mr Octreotide and pituitrin combined treatment, and the control group was only treated with Mr Qu peptide. We compared two groups of effective rate of treatment, the time of hemostasis and adverse reaction characteristics Results In the experimental group with, 38 cases effective, effective rate was 95.0%. The control group of 40 cases with 28 cases effective, effective rate was 70.0%, and the difference is statistically significant. The average hemostasis time is 36.2±10.7h, the average hemostasis time of controls is 48.3±11.6h, and the difference is statistically significant (P<0.05). The incidence of adverse reactions in patients with similar between the two groups has no statistical significance (P>0.05). Conclusion Octreotide and hypophysin have effects on the upper gastrointestinal bleeding. This method could be applied in clinics. |
| Keywords: | Keywords: Octreotide Hypophysin Upper Gastrointestinal Bleeding in Cases Liver Cirrhosis |
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